Schizophrenia is a leading cause of global disability. Current pharmacotherapy for the
disease predominantly uses one mechanism—dopamine D2 receptor blockade—but often …

Abstract Purpose of Review Over the last decade, evidence suggests that a combination of
behavioral and neuroimaging findings can help illuminate changes in functional …

Smell loss has caught public attention during the recent COVID-19 pandemic. Research on
olfactory function in health and disease gains new momentum. Smell deficits have long …

Abstract Background The 22q11. 2 deletion syndrome (22qDel) is a genetic copy number
variant that strongly increases risk for schizophrenia and other neurodevelopmental …

Experience-dependent plasticity in the adult visual system is generally thought of as a
cortical process. However, several recent studies have shown that perceptual learning or …

Theories of the pathophysiology in schizophrenia are converging on the synapse. This
special issue collects papers from leading researchers that suggest a hypothesis that …

Psychiatry is currently negotiating several challenges that are typified by (but are not unique
to) schizophrenia: do periodic refinements in operational diagnostic algorithms (a) resolve …

Background Low-dose lithium (LD-Li) has been shown to rescue cognitive impairment in
mouse models of short-term mild cognitive impairment, dementia, and schizophrenia …

GABAergic cortical interneurons are important components of cortical microcircuits. Their
alterations are associated with a number of neurological and psychiatric disorders, and are …

Background Previous neuroimaging studies indicated that patients with schizophrenia
showed impaired thalamus and thalamo-cortical circuits. However, the dynamic functional …