Diagnostic performance of dual-staining cytology for cervical cancer screening: A systematic literature review

WAA Tjalma - European Journal of Obstetrics & Gynecology and …, 2017 - Elsevier
Cervical cancer screening saves lives. Secondary prevention in cervical cancer screening
relies on the results of primary cytology and/or HPV testing. However, primary screening with …

The role of p16/Ki67 dual staining in cervical cancer screening

A Dovnik, A Repše Fokter - Current Issues in Molecular Biology, 2023 - mdpi.com
Cervical cancer screening has enabled a decrease in the incidence and mortality of cervical
cancer. Various screening modalities have been studied to date. In many countries …

Prospective evaluation of p16/Ki‐67 dual‐stained cytology for managing women with abnormal Papanicolaou cytology: PALMS study results

C Bergeron, H Ikenberg, M Sideri, K Denton… - Cancer …, 2015 - Wiley Online Library
BACKGROUND Testing for the presence of the human papillomavirus (HPV) is widely
accepted for triaging Papanicolaou cytology results categorized as atypical squamous cells …

Meta‐analysis of the accuracy of p16 or p16/Ki‐67 immunocytochemistry versus HPV testing for the detection of CIN2+/CIN3+ in triage of women with minor abnormal …

E Peeters, N Wentzensen, C Bergeron… - Cancer …, 2019 - Wiley Online Library
Background Women with atypical squamous cells of undetermined significance (ASC‐US)
can be triaged accurately with a high‐risk human papillomavirus (hrHPV) test to identify …

[HTML][HTML] Evaluation of p16/Ki-67 dual-stained cytology as triage test for high-risk human papillomavirus-positive women

RMF Ebisch, J Van Der Horst, M Hermsen… - Modern Pathology, 2017 - Elsevier
The aim of this study was to evaluate the clinical utility of p16/Ki-67 dual staining, for the
identification of CIN in high-risk HPV-positive women from a non-responder screening …

Diagnostic accuracy of cervical pap smear and colposcopy in detecting premalignant and malignant lesions of cervix

F Najib, M Hashemi, Z Shiravani, T Poordast… - Indian journal of surgical …, 2020 - Springer
The objective of this study was to determine the diagnostic accuracy of pap smear and
colposcopy in detecting the premalignant and malignant lesion of the cervix. In this cross …

Principles of analytic validation of immunohistochemical assays: guideline update

JD Goldsmith, ML Troxell… - … of pathology & …, 2024 - meridian.allenpress.com
Context.—In 2014, the College of American Pathologists developed an evidence-based
guideline to address analytic validation of immunohistochemical assays. Fourteen …

Predictive value of p16/Ki-67 immunocytochemistry for triage of women with abnormal Papanicolaou test in cervical cancer screening: a systematic review and meta …

CC Chen, LW Huang, CH Bai, CC Lee - Annals of Saudi medicine, 2016 - annsaudimed.net
BACKGROUND: The Papanicolaou (Pap) test is one screening strategy used to prevent
cervical cancer in developed countries. The p16/Ki-67 immunocytochemistry is a triage test …

Dual staining for p16/Ki67 is a more specific test than cytology for triage of HPV-positive women

C Areán-Cuns, M Mercado-Gutiérrez… - Virchows Archiv, 2018 - Springer
Globally, cervical cancer (CC) screening is moving from cytology-based to HPV screening or
a combination of both (co-testing). Most HPV-positive women clear the virus and do not …

Role of cervical cancer biomarkers p16 and Ki67 in abnormal cervical cytological smear

M Gothwal, A Nalwa, P Singh, G Yadav, M Bhati… - The Journal of Obstetrics …, 2021 - Springer
Introduction Cervical cancer is the most common cancer in India. Screening for cervical
cancer helps in marked reduction of invasive cervical cancers. The low sensitivity of …