Thrombosis has long been recognized as a potentially lifethreatening complication in
children with congenital heart disease (CHD), children with acquired heart disease, and in …

Bivalirudin, a direct thrombin inhibitor, is a useful alternative to heparin for anticoagulation in
infants and children. It has been found to be effective in patients requiring treatment of …

Abstract Bivalirudin (Angiomax; The Medicines Company, Parsippany, NJ), a direct thrombin
inhibitor, has found increasing utilization as a heparin alternative in the pediatric population …

Background: Pediatric physicians regularly face the problem of uncertain procedural
anticoagulation in children, especially in neonates. We sought to evaluate the safety, plasma …

Heparin-induced thrombocytopenia is a rare and serious reaction to unfractionated heparin
and low-molecular-weight heparins in children. Quick recognition, discontinuation of …

Objective To determine the safety and efficacy of bivalirudin as an anticoagulant for pediatric
open heart surgery (OHS) and to determine its appropriate dosage for this purpose. Design …

Anticoagulation is an essential component for patients undergoing cardiopulmonary bypass
or extracorporeal membrane oxygenation and for those with ventricular assist devices …

Heparin-induced thrombocytopenia (HIT) can cause life-threatening complications following
the administration of heparin. Discontinuation of all sources of heparin exposure and the use …

Heparin-induced thrombocytopenia (HIT) can occur in children, with the potential for severe
venous and arterial thrombotic complications (Table 21.1). Unlike in adults, few data exist …

Three stage cardiac reconstruction is a common surgical procedure performed in children
with complex cyanotic congenital heart diseases (CCHD) such as hypoplastic left heart …