Since the second version of the Group for Research and Assessment of Psoriasis and
Psoriatic Arthritis (GRAPPA) treatment recommendations were published in 2015 …

The antimalarial hydroxychloroquine (HCQ) has demonstrated several crucial properties for
the treatment of systemic lupus erythematosus (SLE). Herein, we reviewed the main HCQ …

Objective To develop updated guidelines for the pharmacologic management of rheumatoid
arthritis. Methods We developed clinically relevant population, intervention, comparator, and …

Objective To develop evidence-based European Alliance of Associations for Rheumatology
(EULAR) points to consider (PtCs) for the management of difficult-to-treat rheumatoid …

Colchicine is a unique, sophisticated anti-inflammatory agent that has been used for
decades for the prevention of acute inflammatory flares in gout and familial Mediterranean …

Antiphospholipid syndrome (APS) is a thrombo-inflammatory disease propelled by
circulating autoantibodies that recognize cell surface phospholipids and phospholipid …

Background Experimental and clinical evidence support the role of macrophage Toll-like
receptor signaling in maternal anti-SSA/Ro–mediated congenital heart block (CHB) …

Background The rationale behind this update of the 2016 British Society for Rheumatology
(BSR) guidelines on prescribing anti-rheumatic drugs in pregnancy and breastfeeding [1, 2] …

Tumor necrosis factor-alpha (TNF-α) is a multifunctional Th1 cytokine and one of the most
important inflammatory cytokines. In pregnancy, TNF-α influences hormone synthesis …

Background Hydroxychloroquine is generally considered safe in pregnancy for the treatment
of rheumatic conditions, but studies have been too small to evaluate teratogenicity …