DEAD-box ATPases constitute a very large protein family present in all cells, often in great
abundance. From bacteria to humans, they play critical roles in many aspects of RNA …

Eukaryotic ribosome biogenesis involves the synthesis of ribosomal RNA (rRNA) and its
stepwise folding into the unique structure present in mature ribosomes. rRNA folding starts …

ABSTRACT RNA helicases participate in nearly all aspects of RNA metabolism by
rearranging RNAs or RNA–protein complexes in an adenosine triphosphate‐dependent …

In recent years, G-quadruplexes (G4s), types of noncanonical four-stranded nucleic acid
structures, have been identified in many viruses that threaten human health, such as HIV …

The integrated stress response is a network of highly orchestrated pathways activated when
cells are exposed to environmental stressors. While global repression of translation is a well …

RNA helicases—central enzymes in RNA metabolism—often feature intrinsically disordered
regions (IDRs) that enable phase separation and complex molecular interactions. In the …

DDX3 is a multifaceted RNA helicase of the DEAD-box family that plays central roles in all
aspects of RNA metabolism including translation initiation. Here, we provide evidence that …

RNA helicases perform essential housekeeping and regulatory functions in all domains of
life by binding and unwinding RNA molecules. The bacterial RhlE-like DEAD-box RNA …

Medulloblastoma is the most common pediatric brain cancer, with about five cases per
million in the pediatric population. Current treatment strategies have a 5-year survival rate of …

During the sexual phase of Neurospora crassa, unpaired genes are subject to a silencing
mechanism known as meiotic silencing by unpaired DNA (MSUD). MSUD targets the …