Randomised controlled trial on the effect of clomiphene citrate and gonadotropin dose on ovarian response markers and IVF outcomes in poor responders
R Moffat, C Hansali, A Schoetzau, A Ahler… - Human …, 2021 - academic.oup.com
STUDY QUESTION Does the gonadotropin (GN) starting dose and the addition of
clomiphene citrate (CC) during the early follicular phase influence oocyte yield in poor …
clomiphene citrate (CC) during the early follicular phase influence oocyte yield in poor …
Molecular cloning and characterization of STC1 gene and its functional analyses in yak (Bos grunniens) cumulus granulosa cells
X Yang, J Ma, L Mo, Y Xiong, X Xiong, D Lan, W Fu… - Theriogenology, 2023 - Elsevier
Cumulus granulosa cells (CGCs), an important type of ovarian somatic cells, carries out
various functions related to oogenesis, follicular development, and steroidogenesis …
various functions related to oogenesis, follicular development, and steroidogenesis …
Heterozygous gain of function variant in GUCY1A2 may cause autonomous ovarian hyperfunction
T Wittrien, A Ziegler, A Rühle… - European Journal of …, 2024 - academic.oup.com
Purpose The purpose of this study was to characterize the phenotype associated with a de
novo gain-of-function variant in the GUCY1A2 gene. Methods An individual carrying the de …
novo gain-of-function variant in the GUCY1A2 gene. Methods An individual carrying the de …
Regulation of insulin-like growth factor 2 by oocyte-secreted factors in primary human granulosa cells
E Hobeika, M Armouti, MA Fierro… - The Journal of …, 2020 - academic.oup.com
Context Human granulosa cells (hGCs) produce and respond to insulin-like growth factor 2
(IGF2) but whether the oocyte participates in IGF2 regulation in humans is unknown …
(IGF2) but whether the oocyte participates in IGF2 regulation in humans is unknown …
[HTML][HTML] Female-dominant estrogen production in healthy children before adrenarche
M Igarashi, T Ayabe… - Endocrine …, 2021 - ec.bioscientifica.com
Objective Ultra-sensitive hormone assays have detected slight sex differences in blood
estradiol (E 2) levels in young children before adrenarche. However, the origin of circulating …
estradiol (E 2) levels in young children before adrenarche. However, the origin of circulating …
Decreased GDF9 and BMP15 in follicle fluid and granulosa cells and outcomes of IVF-ET among young patients with low prognosis
T Huang, F Chen, Y Zhang, S Chen, F Long… - Journal of Assisted …, 2023 - Springer
Purpose To analyze the level of growth differentiation factor 9 (GDF9) and bone
morphogenetic protein 15 (BMP15) in follicle fluid (FF) and granulosa cells (GCs) derived …
morphogenetic protein 15 (BMP15) in follicle fluid (FF) and granulosa cells (GCs) derived …
[HTML][HTML] Single-Cell Transcriptome Analysis Reveals Development-Specific Networks at Distinct Synchronized Antral Follicle Sizes in Sheep Oocytes
Y Song, N Zhang, Y Zhang, J Wang, Q Lv… - International Journal of …, 2024 - mdpi.com
The development of the ovarian antral follicle is a complex, highly regulated process.
Oocytes orchestrate and coordinate the development of mammalian ovarian follicles, and …
Oocytes orchestrate and coordinate the development of mammalian ovarian follicles, and …
Moxibustion ameliorates ovarian function in premature ovarian insufficiency rats by activating cAMP/PKA/CREB to promote steroidogenesis in ovarian granulosa cells
R Zhao, L Ran, H Yao, Y He, X Lu, W Zhu… - The Journal of Steroid …, 2024 - Elsevier
Premature ovarian insufficiency (POI) presents a substantial challenge to women's
physiological and psychological well-being. Hormone replacement therapy, as the preferred …
physiological and psychological well-being. Hormone replacement therapy, as the preferred …
Non-canonical cyclic AMP SMAD1/5/8 signalling in human granulosa cells
MJ Bertoldo, MY Cheung, ZK Sia, D Agapiou… - Molecular and cellular …, 2019 - Elsevier
Abstract Development of mammalian ovarian follicles is promoted by the combined action of
endocrine cues and paracrine factors. Follicle stimulating hormone (FSH), through the action …
endocrine cues and paracrine factors. Follicle stimulating hormone (FSH), through the action …
Salt-inducible kinases are critical determinants of female fertility
M Armouti, N Winston, O Hatano, E Hobeika… - …, 2020 - academic.oup.com
Follicle development is the most crucial step toward female fertility and is controlled mainly
by follicle-stimulating hormone (FSH). In ovarian granulosa cells (GCs), FSH activates …
by follicle-stimulating hormone (FSH). In ovarian granulosa cells (GCs), FSH activates …