Vitamin K2 enhances the tumor suppressive effects of 1, 25 (OH) 2D3 in triple negative breast cancer cells
CJ Narvaez, MJ Bak, N Salman, JE Welsh - The Journal of Steroid …, 2023 - Elsevier
K vitamins are well known as essential cofactors for hepatic γ-carboxylation of coagulation
factors, but their potential role in chronic diseases including cancer is understudied. K2, the …
factors, but their potential role in chronic diseases including cancer is understudied. K2, the …
[HTML][HTML] Dual effect of vitamin D3 on breast cancer-associated fibroblasts
N Łabędź, A Anisiewicz, M Stachowicz-Suhs, J Banach… - BMC cancer, 2024 - Springer
Abstract Background Cancer-associated fibroblasts (CAFs) play an important role in the
tumor microenvironment. Despite the well-known in vitro antitumoral effect of vitamin D3 …
tumor microenvironment. Despite the well-known in vitro antitumoral effect of vitamin D3 …
[HTML][HTML] Course of Vitamin D Levels in Newly Diagnosed Non-Metastatic Breast Cancer Patients over One Year with Quarterly Controls and Substitution
C Zemlin, L Altmayer, M Lang, JT Schleicher, C Stuhlert… - Nutrients, 2024 - mdpi.com
(1) Background: Vitamin D levels in patients remain inadequately understood, with research
yielding inconsistent findings. Breast cancer patients, particularly due to oncological …
yielding inconsistent findings. Breast cancer patients, particularly due to oncological …
[HTML][HTML] Serum 25-Hydroxyvitamin D Is Inversely Associated with Nasopharyngeal Carcinoma: A Hospital-Based Matched Case–Control Study in Malaysia
V Ulaganathan, MS Lye, SP Loh, YY Yap, M Kandiah… - Nutrients, 2024 - mdpi.com
Serum 25 (OH) D deficiency consistently demonstrated molecular mechanisms through
which chronic inflammation is associated with the risk of nasopharyngeal carcinoma (NPC) …
which chronic inflammation is associated with the risk of nasopharyngeal carcinoma (NPC) …
[HTML][HTML] The Combination of the CDK4/6 Inhibitor, Palbociclib, With the Vitamin D3 Analog, Inecalcitol, Has Potent In Vitro and In Vivo Anticancer Effects in Hormone …
J Vanhevel, L Verlinden, S Loopmans… - Frontiers in …, 2022 - frontiersin.org
Active vitamin D3, 1, 25-dihydroxyvitamin D3 [1, 25 (OH) 2D3], and its synthetically derived
analogs possess potent anticancer properties. In breast cancer (BC) cells, 1, 25 (OH) 2D3 …
analogs possess potent anticancer properties. In breast cancer (BC) cells, 1, 25 (OH) 2D3 …
Vitamin D Receptor Expression Is Significantly Decreased in Bone Metastases Compared to Matched Primary Breast Cancer Tumours
K Horas, M Abraham, R Ebert… - Cancer …, 2023 - Taylor & Francis
There is ample evidence today that vitamin D signalling via the vitamin D receptor (VDR)
plays a pivotal role in cancer growth and metastasis. The aim of this study was to analyse …
plays a pivotal role in cancer growth and metastasis. The aim of this study was to analyse …
[HTML][HTML] The Vitamin D Receptor as a Prognostic Marker in Breast Cancer—A Cohort Study
L Huss, I Gulz-Haake, E Nilsson, H Tryggvadottir… - Nutrients, 2024 - mdpi.com
Previous research has indicated an association between the presence of the vitamin D
receptor (VDR) in breast cancer tissue and a favorable prognosis. This study aimed to …
receptor (VDR) in breast cancer tissue and a favorable prognosis. This study aimed to …
[HTML][HTML] Vitamin D in Melanoma: Potential Role of Cytochrome P450 Enzymes
M Ben-Eltriki, EJ Gayle, JM Paras, L Nyame-Addo… - Life, 2024 - mdpi.com
Vitamin D is a promising anticancer agent for the prevention and treatment of several
cancers, including melanoma. Low 25-hydroxyvitamin D levels, a routinely used marker for …
cancers, including melanoma. Low 25-hydroxyvitamin D levels, a routinely used marker for …
[HTML][HTML] Vitamin D and Its Metabolites Status before and during Chemotherapy in Caucasian Breast Cancer Patients
M Kimsa-Furdzik, A Bednarek, G Hibner… - Metabolites, 2023 - mdpi.com
Background: The predictive role of vitamin D (VD) in breast cancer (BC) patients' survival is
still being investigated. This paper aims to evaluate the changes in VD metabolites during …
still being investigated. This paper aims to evaluate the changes in VD metabolites during …
Design, synthesis and evaluation of side-chain hydroxylated derivatives of lithocholic acid as potent agonists of the vitamin D receptor (VDR)
CM González, S Gaikwad, G Lasanta, J Loureiro… - Bioorganic …, 2021 - Elsevier
A high number of biologically active and low-calcemic secosteroidal ligands of the vitamin D
receptor (VDR) have been developed, some of which are already used clinically although …
receptor (VDR) have been developed, some of which are already used clinically although …