[HTML][HTML] Autoimmune disorders of the nervous system: pathophysiology, clinical features, and therapy

S Bhagavati - Frontiers in neurology, 2021 - frontiersin.org
Remarkable discoveries over the last two decades have elucidated the autoimmune basis of
several, previously poorly understood, neurological disorders. Autoimmune disorders of the …

Brain injury in COVID-19 is associated with dysregulated innate and adaptive immune responses

EJ Needham, AL Ren, RJ Digby, EJ Norton, S Ebrahimi… - Brain, 2022 - academic.oup.com
COVID-19 is associated with neurological complications including stroke, delirium and
encephalitis. Furthermore, a post-viral syndrome dominated by neuropsychiatric symptoms …

Immunoglobulins with non-canonical functions in inflammatory and autoimmune disease states

EA Ermakov, GA Nevinsky, VN Buneva - International journal of molecular …, 2020 - mdpi.com
Immunoglobulins are known to combine various effector mechanisms of the adaptive and
the innate immune system. Classical immunoglobulin functions are associated with antigen …

Endogenous retroviruses in nervous system disorders

V Gröger, A Emmer, MS Staege, H Cynis - Pharmaceuticals, 2021 - mdpi.com
Human endogenous retroviruses (HERV) have been implicated in the pathogenesis of
several nervous system disorders including multiple sclerosis and amyotrophic lateral …

Following Natural Autoantibodies: Further Immunoserological Evidence Regarding Their Silent Plasticity and Engagement in Immune Activation

D Szinger, T Berki, P Németh, S Erdo-Bonyar… - International journal of …, 2023 - mdpi.com
Contradictory reports are available on vaccine-associated hyperstimulation of the immune
system, provoking the formation of pathological autoantibodies. Despite being …

Potential causal role of synovial complement system activation in the development of post-traumatic osteoarthritis after anterior cruciate ligament injury or meniscus …

VM Holers, RM Frank, A Clauw, J Seifert… - Frontiers in …, 2023 - frontiersin.org
Anterior cruciate ligament (ACL) injury and meniscal tear (MT) are major causal factors for
developing post-traumatic osteoarthritis (PTOA), but the biological mechanism (s) are …

N-Glycosylation of the Ig Receptors Shapes the Antigen Reactivity in Chronic Lymphocytic Leukemia Subset #201

A Iatrou, M Gounari, E Sofou… - The Journal of …, 2023 - journals.aai.org
Subset# 201 is a clinically indolent subgroup of patients with chronic lymphocytic leukemia
defined by the expression of stereotyped, mutated IGHV4-34/IGLV1-44 BCR Ig. Subset# 201 …

Autophagy: A new concept in autoimmunity regulation and a novel therapeutic option

SR Bonam, F Wang, S Muller - Journal of autoimmunity, 2018 - Elsevier
Nowadays, pharmacologic treatments of autoinflammatory diseases are largely palliative
rather than curative. Most of them result in non-specific immunosuppression, which can be …

A novel model of cancer drug resistance: oncosomal release of cytotoxic and antibody-based drugs

T Eguchi, EA Taha, SK Calderwood, K Ono - Biology, 2020 - mdpi.com
Extracellular vesicles (EVs), such as exosomes or oncosomes, often carry oncogenic
molecules derived from tumor cells. In addition, accumulating evidence indicates that tumor …

Insights from single cell RNA sequencing into the immunology of type 1 diabetes-cell phenotypes and antigen specificity

SJ Hanna, D Tatovic, TC Thayer… - Frontiers in immunology, 2021 - frontiersin.org
In the past few years, huge advances have been made in techniques to analyse cells at an
individual level using RNA sequencing, and many of these have precipitated exciting …