DNA methylation (DNAm)–an epigenetic process that regulates gene expression–may
represent a mechanism for the biological embedding of early traumatic experiences …

Major depressive disorder (MDD) is a chronic, generally episodic and debilitating disease
that affects an estimated 300 million people worldwide, but its pathogenesis is poorly …

Mental disorders are highly complex and multifactorial in origin, comprising an elaborate
interplay of genetic and environmental factors. Epigenetic mechanisms such as DNA …

There is substantial variation in people's responses to adversity, with a considerable
proportion of individuals displaying psychological resilience. Epigenetic mechanisms are …

Objective: There is growing evidence that exposure to trauma prior to conception can affect
offspring. The authors have reported that adult offspring of Holocaust survivors showed …

Polycystic ovary syndrome (PCOS) is a common endocrine disease in females that is
characterized by hyperandrogenemia, chronic anovulation, and polycystic ovaries …

Genetic and early environmental factors are interwoven in the etiology of Borderline
Personality Disorder (BPD). Epigenetic mechanisms offer the molecular machinery to adapt …

Stress-induced mental health disorders are affecting many people around the world.
However, effective drug therapy for curing psychiatric diseases does not occur sufficiently …

Background Less than half of all individuals with post-traumatic stress disorder (PTSD) remit
spontaneously and a large proportion of those seeking treatment do not respond sufficiently …

Previous research suggests that childhood maltreatment is associated with epigenetic
modification of genes involved in hypothalamic-pituitary-adrenal (HPA) functioning, which …