Pharmacokinetics, tissue distribution, and druggability prediction of the natural anticancer active compound cytisine n-isoflavones combined with computer simulation

F Chen, X Yin, Y Wang, Y Lv, S Sheng… - Biological and …, 2020 - jstage.jst.go.jp
Abstract Cytisine N-methylene-(5, 7-dihydroxy-4′-methoxy)-isoflavone (CNF2) is a new
compound isolated from the Chinese herbal medicine Sophora alopecuroides. Preliminary …

The fate of quinolizidine alkaloids during the processing of lupins (Lupinus spp.) for human consumption

S Schryvers, C Arinzechukwu, B Miserez, M Eeckhout… - Food Chemistry, 2023 - Elsevier
Lupin, a protein-rich grain legume, and products thereof, are becoming increasingly
important in our diets. However, variable and high concentrations of quinolizidine alkaloids …

Analysis and identification of chemical constituents of fenugreek by UPLC-IT-MS n and UPLC-Q-TOF-MS

J Wang, W Jiang, Z Liu, J Wang, T Fu… - Chemical Research in …, 2017 - Springer
Fenugreek, a traditional Chinese medical plant, has been widely used as food ingredients
because of its outstanding medicinal qualities. The hypoglycemic activity of fenugreek is one …

Comparison of various chromatographic systems for analysis of cytisine in human serum, saliva and pharmaceutical formulation by HPLC with diode array …

K Wróblewski, A Petruczynik, T Tuzimski, D Przygodzka… - Molecules, 2019 - mdpi.com
Background: Identification and quantitative determination of cytisine, especially in biological
samples and pharmaceutical formulations, is still a difficult analytical task. Cytisine is an …

Quick and reliable determination of matrine and oxymatrine in vegetable products by Liquid Chromatography and Mass Spectrometry

D Nardiello, WMV Marchesiello, S Sportelli… - Journal of Food …, 2022 - Elsevier
Abstract A rapid LC/tandem MS method for the quantitative determination of matrine-based
biopesticides is proposed for the analysis of fruit and vegetable samples. A simple extraction …

Transcriptome-Based Identification of the SaR2R3-MYB Gene Family in Sophora alopecuroides and Function Analysis of SaR2R3-MYB15 in Salt Stress Tolerance

Y Wang, X Yang, Y Hu, X Liu, T Shareng, G Cao… - Plants, 2024 - mdpi.com
As one of the most prominent gene families, R2R3-MYB transcription factors significantly
regulate biochemical and physiological processes under salt stress. However, in Sophora …

Combination of chemical profiling and network pharmacology analysis to investigate the potential mechanism of Li‐Zhong‐Xiao‐Pi granules in the treatment of gastric …

C Liu, H Chen, Y Zhang, M Li, Q Jiang… - Biomedical …, 2023 - Wiley Online Library
Abstract Li‐Zhong‐Xiao‐Pi granules (LZXP) are effective for treating gastric precancerous
lesions (GPL) in traditional Chinese medicine. However, the active compounds of LZXP and …

Analysis and Identification of the Chemical Constituents of Ding‐Zhi‐Xiao‐Wan Prescription by HPLC‐IT‐MSn and HPLC‐Q‐TOF‐MS

S Tang, S Liu, Z Liu, F Song… - Chinese Journal of …, 2015 - Wiley Online Library
Abstract Ding‐Zhi‐Xiao‐Wan (DZXW) is a famous traditional Chinese medicine (TCM)
formula, which is composed of four herbs, Ginseng Radix, Poria, Polygala Radix and Acori …

Development and validation of a hydrophilic interaction ultra‐high‐performance liquid chromatography with triple quadrupole MS/MS for the absolute and relative …

H Wang, J Duan, S Guo, D Qian… - Journal of separation …, 2013 - Wiley Online Library
Amino acids are naturally occurring compounds in many edible or medicinal plants, which
possess a variety of pharmacological effects on humans. The aim of this study is to develop …

Comparative analysis of bioactive constituents and pharmacological activities from different parts of Nauclea officinalis

M Zhou, Z Xie, W Guan, J Zhang - Biomedical Chromatography, 2021 - Wiley Online Library
The stems of Nauclea officinalis have been utilized as a crude drug in China, so other parts
of the plant are abandoned, resulting in a waste of traditional Chinese medicine resources …