Antithyroid drugs and their analogues: synthesis, structure, and mechanism of action

D Manna, G Roy, G Mugesh - Accounts of chemical research, 2013 - ACS Publications
Thyroid hormones are essential for the development and differentiation of all cells of the
human body. They regulate protein, fat, and carbohydrate metabolism. In this Account, we …

[HTML][HTML] Selenium—more than just a fortuitous sulfur substitute in redox biology

LB Maia, BK Maiti, I Moura, JJG Moura - Molecules, 2023 - mdpi.com
Living organisms use selenium mainly in the form of selenocysteine in the active site of
oxidoreductases. Here, selenium's unique chemistry is believed to modulate the reaction …

A mouse model for hereditary thyroid dysgenesis and cleft palate

M De Felice, C Ovitt, E Biffali, A Rodriguez-Mallon… - Nature …, 1998 - nature.com
Alteration of thyroid gland morphogenesis (thyroid dysgenesis) is a frequent human
malformation. Among the one in three to four thousand newborns in which congenital …

[HTML][HTML] Werner and Ingbar's the thyroid: a fundamental and clinical text

P Kopp, DS Cooper, LE Braverman - 2020 - doctorlib.info
Thyroid hormone biosynthesis, storage, and secretion require a series of highly regulated
steps. Iodide, the rate-limiting substrate for thyroid hormone synthesis, is actively transported …

4B Thyroid hormone synthesis

P Kopp - Werner & Ingbar's The Thyroid: A Fundamental and …, 2005 - books.google.com
Thyroid hormone biosynthesis, storage, and secretion require a series of highly regulated
steps. Iodide, the ratelimiting substrate for thyroid hormone synthesis, is actively transported …

Serum thyroglobulin measurement: utility in clinical practice

JI Torréns, HB Burch - Endocrinology and metabolism clinics of North …, 2001 - Elsevier
Serum thyroglobulin measurement is essential in the diagnosis and follow-up of several
thyroid disorders. This is especially the case in the management of differentiated thyroid …

Theoretical and experimental study for the biomimetic recognition of levothyroxine hormone on magnetic molecularly imprinted polymer

SL Moura, LM Fajardo, L dos Anjos Cunha… - Biosensors and …, 2018 - Elsevier
This study addresses the rational design of a magnetic molecularly imprinted polymer
(magnetic-MIP) for the selective recognition of the hormone levothyroxine. The theoretical …

Trace elements status in multinodular goiter

B Giray, J Arnaud, İ Sayek, A Favier, F Hıncal - Journal of trace elements in …, 2010 - Elsevier
Importance of iodine and selenium in thyroid metabolism is well known, but the roles of other
essential trace elements including copper, zinc, manganese and iron on thyroid hormone …

Thyroidal effects of di-(2-ethylhexyl) phthalate in rats of different selenium status

P Erkekoglu, B Kocer-Gumusel… - Journal of …, 2012 - dl.begellhouse.com
This study was designed to investigate the effects of di-(2-ethylhexyl) phthalate (DEHP) on
thyroid hormone levels and oxidant/antioxidant parameters in the rat and to evaluate the …

Halogen‐bonding interactions of polybrominated diphenyl ethers and thyroid hormone derivatives: A potential mechanism for the inhibition of iodothyronine …

ES Marsan, CA Bayse - Chemistry–A European Journal, 2017 - Wiley Online Library
Polybrominated diphenyl ethers (PBDEs) increase flame resistance in consumer goods, but
these compounds and their hydroxylated derivatives (OH‐BDEs) impair normal thyroid …