The dawn of a new era: targeting the “undruggables” with antibody-based therapeutics
The high selectivity and affinity of antibodies toward their antigens have made them a highly
valuable tool in disease therapy, diagnosis, and basic research. A plethora of chemical and …
valuable tool in disease therapy, diagnosis, and basic research. A plethora of chemical and …
[HTML][HTML] Functionalized liposomes for targeted breast cancer drug delivery
Despite the exceptional progress in breast cancer pathogenesis, prognosis, diagnosis, and
treatment strategies, it remains a prominent cause of female mortality worldwide …
treatment strategies, it remains a prominent cause of female mortality worldwide …
[HTML][HTML] Recent advancements in polymer/liposome assembly for drug delivery: From surface modifications to hybrid vesicles
Liposomes are consolidated and attractive biomimetic nanocarriers widely used in the field
of drug delivery. The structural versatility of liposomes has been exploited for the …
of drug delivery. The structural versatility of liposomes has been exploited for the …
[HTML][HTML] Recent advances in sensing the inter-biomolecular interactions at the nanoscale–A comprehensive review of AFM-based force spectroscopy
Biomolecular interactions underpin most processes inside the cell. Hence, a precise and
quantitative understanding of molecular association and dissociation events is crucial, not …
quantitative understanding of molecular association and dissociation events is crucial, not …
Innovative nanomaterials for cancer diagnosis, imaging, and therapy: Drug delivery applications
M Pourmadadi, MM Eshaghi, S Ostovar… - Journal of Drug Delivery …, 2023 - Elsevier
The emergence of nanomedicine drugs as a result of the fast advancement of
nanotechnology offers enormous potential for improving cancer treatment strategies. The …
nanotechnology offers enormous potential for improving cancer treatment strategies. The …
Injectable amphipathic artesunate prodrug‐hydrogel microsphere as gene/drug nano‐microplex for rheumatoid arthritis therapy
Artemisinin and its derivatives (artemisinins) are first‐line chemotherapeutic agents of lethal
malaria, which also showed tremendous value in many other diseases including chronic …
malaria, which also showed tremendous value in many other diseases including chronic …
[HTML][HTML] Organically derived exosomes as carriers of anticancer drugs and imaging agents for cancer treatment
A Srivastava, S Rathore, A Munshi… - Seminars in cancer biology, 2022 - Elsevier
Extracellular vesicles (EVs), is the umbrella term used for different types of vesicles
produced by the cells, among which exosomes form the largest group. Exosomes perform …
produced by the cells, among which exosomes form the largest group. Exosomes perform …
[HTML][HTML] Sequential delivery of PD-1/PD-L1 blockade peptide and IDO inhibitor for immunosuppressive microenvironment remodeling via an MMP-2 responsive dual …
C Hu, Y Song, Y Zhang, S He, X Liu, X Yang… - … Pharmaceutica Sinica B, 2023 - Elsevier
Intelligent responsive drug delivery system opens up new avenues for realizing safer and
more effective combination immunotherapy. Herein, a kind of tumor cascade-targeted …
more effective combination immunotherapy. Herein, a kind of tumor cascade-targeted …
[HTML][HTML] Nanoparticles advanced from preclinical studies to clinical trials for lung cancer therapy
Y Liu, W Cheng, HY Xin, R Liu, Q Wang, W Cai… - Cancer …, 2023 - Springer
Lung cancer is the leading cause of cancer mortality. As a heterogeneous disease, it has
different subtypes and various treatment modalities. In addition to conventional surgery …
different subtypes and various treatment modalities. In addition to conventional surgery …
[HTML][HTML] Research progress in inducing immunogenic cell death of tumor cells
D Xie, Q Wang, G Wu - Frontiers in immunology, 2022 - frontiersin.org
Immunogenic cell death (ICD) is a regulated cell death (RCD) pathway. In response to
physical and chemical signals, tumor cells activate specific signaling pathways that stimulate …
physical and chemical signals, tumor cells activate specific signaling pathways that stimulate …