Risk of colorectal cancer in inflammatory bowel diseases
Inflammatory bowel diseases (IBDs) are chronic problems of gastrointestinal tract (GIT) with
poorly understood aetiology. Patients with any of the two common entities, Crohn's disease …
poorly understood aetiology. Patients with any of the two common entities, Crohn's disease …
[HTML][HTML] Glutamine metabolism in macrophages: a novel target for obesity/type 2 diabetes
Obesity is a nutritional disorder resulting from a chronic imbalance between energy intake
and expenditure. This disease is characterized by inflammation in multiple cell types …
and expenditure. This disease is characterized by inflammation in multiple cell types …
Tiliroside Ameliorates Ulcerative Colitis by Restoring the M1/M2 Macrophage Balance via the HIF-1α/glycolysis Pathway
H Zhuang, Q Lv, C Zhong, Y Cui, L He… - Frontiers in …, 2021 - frontiersin.org
Macrophages polarized to different phenotypes critically contribute to colitis development by
coordinating inflammatory and anti-inflammatory processes. Herein, targeting the balance …
coordinating inflammatory and anti-inflammatory processes. Herein, targeting the balance …
Development of functional resident macrophages in human pluripotent stem cell-derived colonic organoids and human fetal colon
Most organs have tissue-resident immune cells. Human organoids lack these immune cells,
which limits their utility in modeling many normal and disease processes. Here, we describe …
which limits their utility in modeling many normal and disease processes. Here, we describe …
Immunoregulation of macrophages by dynamic ligand presentation via ligand–cation coordination
Macrophages regulate host responses to implants through their dynamic adhesion, release,
and activation. Herein, we employ bisphosphonate (BP)-coated gold nanoparticle template …
and activation. Herein, we employ bisphosphonate (BP)-coated gold nanoparticle template …
Macrophage polarization in inflammatory bowel disease
K Zhang, J Guo, W Yan, L Xu - Cell Communication and Signaling, 2023 - Springer
The growing prevalence of inflammatory bowel disease (IBD) has encouraged research
efforts, which have contributed to gradual improvements in our understanding of IBD …
efforts, which have contributed to gradual improvements in our understanding of IBD …
Structural differences of polysaccharides from Astragalus before and after honey processing and their effects on colitis mice
J Wu, C Li, L Bai, J Wu, R Bo, M Ye, L Huang… - International Journal of …, 2021 - Elsevier
Honey-processed Astragalus is a dosage form of Radix Astragali processed with honey,
which exhibits better efficacy of tonifying Qi than the raw product. Polysaccharides are its …
which exhibits better efficacy of tonifying Qi than the raw product. Polysaccharides are its …
Gut-resident CX3CR1hi macrophages induce tertiary lymphoid structures and IgA response in situ
B Koscsó, S Kurapati, RR Rodrigues, J Nedjic… - Science …, 2020 - science.org
Intestinal mononuclear phagocytes (MPs) are composed of heterogeneous dendritic cell
(DC) and macrophage subsets necessary for the initiation of immune response and control …
(DC) and macrophage subsets necessary for the initiation of immune response and control …
Protocadherin 20 maintains intestinal barrier function to protect against Crohn's disease by targeting ATF6
S Huang, Z Xie, J Han, H Wang, G Yang, M Li, G Zhou… - Genome Biology, 2023 - Springer
Background Intestinal barrier dysfunction plays a central role in the pathological onset of
Crohn's disease. We identify the cadherin superfamily member protocadherin 20 (PCDH20) …
Crohn's disease. We identify the cadherin superfamily member protocadherin 20 (PCDH20) …
Understanding immunoactinopathies: A decade of research on WAS gene defects
RC Vieira, LG Pinho… - Pediatric Allergy and …, 2023 - Wiley Online Library
Immunoactinopathies caused by mutations in actin‐related proteins are a growing group of
inborn errors of immunity (IEI). Immunoactinopathies are caused by a dysregulated actin …
inborn errors of immunity (IEI). Immunoactinopathies are caused by a dysregulated actin …