Contemporary risk of surgery in patients with ulcerative colitis and Crohn's disease: a meta-analysis of population-based cohorts

L Tsai, C Ma, PS Dulai, LJ Prokop, S Eisenstein… - Clinical …, 2021 - Elsevier
Background & Aims We conducted a systematic review with meta-analysis to estimate rates
and trends of colectomy in patients with ulcerative colitis (UC), and of primary and re …

Is it time to include older adults in inflammatory bowel disease trials? A call for action

S Vieujean, B Caron, V Jairath, A Benetos… - The Lancet Healthy …, 2022 - thelancet.com
The therapeutic management of older patients with inflammatory bowel disease (IBD) is
challenging, particularly because of the absence of evidence-based guidelines for these …

The impact of inflammatory bowel disease in Canada 2018: epidemiology

GG Kaplan, CN Bernstein, S Coward… - Journal of the …, 2019 - academic.oup.com
Canada has among the highest incidence and prevalence of inflammatory bowel disease
(IBD) in the world. After decades of rising incidence of IBD in Canada during the 20th …

Incidence and treatment of patients diagnosed with inflammatory bowel diseases at 60 years or older in Sweden

ÅH Everhov, J Halfvarson, P Myrelid, MC Sachs… - Gastroenterology, 2018 - Elsevier
Background & Aims Diagnosis of inflammatory bowel diseases (IBD) is increasing among
elderly persons (60 years or older). We performed a nationwide population-based study to …

Pretreatment frailty is independently associated with increased risk of infections after immunosuppression in patients with inflammatory bowel diseases

B Kochar, W Cai, A Cagan, AN Ananthakrishnan - Gastroenterology, 2020 - Elsevier
Background & Aims Infections are an important adverse effect of immunosuppression for
treatment of inflammatory bowel diseases (IBDs). However, risk of infection cannot be …

Are neurodegenerative diseases associated with an increased risk of inflammatory bowel disease? A two-sample Mendelian randomization study

G Cui, S Li, H Ye, Y Yang, Q Huang, Y Chu… - Frontiers in …, 2022 - frontiersin.org
Background Several studies have shown that neurodegenerative diseases (eg, Parkinson's
disease [PD] and Alzheimer's disease [AD]) are associated with inflammatory bowel disease …

The impact of inflammatory bowel disease in Canada 2018: direct costs and health services utilization

ME Kuenzig, EI Benchimol, L Lee… - Journal of the …, 2019 - academic.oup.com
Direct health care costs of illness reflect the costs of medically necessary services and
treatments paid for by public and private payers, including hospital-based care, outpatient …

Mortality in adult-onset and elderly-onset IBD: a nationwide register-based cohort study 1964–2014

O Olén, J Askling, MC Sachs, M Neovius, KE Smedby… - Gut, 2020 - gut.bmj.com
Objectives To examine all-cause and cause-specific mortality in adult-onset and elderly-
onset IBD and to describe time trends in mortality over the past 50 years. Design Swedish …

Frailty in inflammatory bowel diseases: an emerging concept

B Kochar, AR Orkaby… - Therapeutic …, 2021 - journals.sagepub.com
Inflammatory bowel diseases (IBD), consisting of Crohn's disease and ulcerative colitis, are
chronic remitting, relapsing inflammatory conditions of the gastrointestinal tract. While …

Frailty is independently associated with mortality in 11 001 patients with inflammatory bowel diseases

B Kochar, W Cai, A Cagan… - Alimentary …, 2020 - Wiley Online Library
Background The prevalence of older adults with inflammatory bowel diseases (IBD) is
increasing. Frailty is an important predictor of outcomes in many chronic disease states. The …