The leukaemia stem cell: similarities, differences and clinical prospects in CML and AML
For two decades, leukaemia stem cells (LSCs) in chronic myeloid leukaemia (CML) and
acute myeloid leukaemia (AML) have been advanced paradigms for the cancer stem cell …
acute myeloid leukaemia (AML) have been advanced paradigms for the cancer stem cell …
The chronic myeloid leukemia stem cell: stemming the tide of persistence
TL Holyoake, D Vetrie - Blood, The Journal of the American …, 2017 - ashpublications.org
Chronic myeloid leukemia (CML) is caused by the acquisition of the tyrosine kinase BCR-
ABL1 in a hemopoietic stem cell, transforming it into a leukemic stem cell (LSC) that self …
ABL1 in a hemopoietic stem cell, transforming it into a leukemic stem cell (LSC) that self …
Critical reevaluation of endothelial progenitor cell phenotypes for therapeutic and diagnostic use
GP Fadini, D Losordo, S Dimmeler - Circulation research, 2012 - Am Heart Assoc
Diverse subsets of endothelial progenitor cells (EPCs) are used for the treatment of ischemic
diseases in clinical trials, and circulating EPCs levels are considered as biomarkers for …
diseases in clinical trials, and circulating EPCs levels are considered as biomarkers for …
Transdifferentiation of glioblastoma cells into vascular endothelial cells
Y Soda, T Marumoto… - Proceedings of the …, 2011 - National Acad Sciences
Glioblastoma (GBM) is the most malignant brain tumor and is highly resistant to intensive
combination therapies and anti-VEGF therapies. To assess the resistance mechanism to anti …
combination therapies and anti-VEGF therapies. To assess the resistance mechanism to anti …
Redefining endothelial progenitor cells via clonal analysis and hematopoietic stem/progenitor cell principals
The limited vessel-forming capacity of infused endothelial progenitor cells (EPCs) into
patients with cardiovascular dysfunction may be related to a misunderstanding of the …
patients with cardiovascular dysfunction may be related to a misunderstanding of the …
Mobilization of endothelial progenitor cells in patients with acute myocardial infarction
S Shintani, T Murohara, H Ikeda, T Ueno, T Honma… - Circulation, 2001 - Am Heart Assoc
Background—Endothelial progenitor cells (EPCs) circulate in adult peripheral blood (PB)
and contribute to neovascularization. However, little is known regarding whether EPCs and …
and contribute to neovascularization. However, little is known regarding whether EPCs and …
Normal and leukemic hematopoiesis: are leukemias a stem cell disorder or a reacquisition of stem cell characteristics?
E Passegué, CHM Jamieson… - Proceedings of the …, 2003 - National Acad Sciences
Leukemia can be viewed as a newly formed, abnormal hematopoietic tissue initiated by a
few leukemic stem cells (LSCs) that undergo an aberrant and poorly regulated process of …
few leukemic stem cells (LSCs) that undergo an aberrant and poorly regulated process of …
[HTML][HTML] Leukemia stem cells and microenvironment: biology and therapeutic targeting
MY Konopleva, CT Jordan - Journal of clinical oncology, 2011 - ncbi.nlm.nih.gov
Acute myelogenous leukemia is propagated by a subpopulation of leukemia stem cells
(LSCs). In this article, we review both the intrinsic and extrinsic components that are known …
(LSCs). In this article, we review both the intrinsic and extrinsic components that are known …
Abundant progenitor cells in the adventitia contribute to atherosclerosis of vein grafts in ApoE-deficient mice
Y Hu, Z Zhang, E Torsney, AR Afzal… - The Journal of …, 2004 - Am Soc Clin Investig
Recent evidence indicates that vascular progenitor cells may be the source of smooth
muscle cells (SMCs) that accumulate in atherosclerotic lesions, but the origin of these …
muscle cells (SMCs) that accumulate in atherosclerotic lesions, but the origin of these …
Endothelial progenitor cells for postnatal vasculogenesis
T Asahara, A Kawamoto - American Journal of Physiology …, 2004 - journals.physiology.org
In the past decade, researchers have defined committed stem or progenitor cells from
various tissues, including bone marrow, peripheral blood, brain, liver, and reproductive …
various tissues, including bone marrow, peripheral blood, brain, liver, and reproductive …