[HTML][HTML] Chronic myeloid leukemia stem cells in the era of targeted therapies: resistance, persistence and long-term dormancy

JC Chomel, AG Turhan - Oncotarget, 2011 - ncbi.nlm.nih.gov
Targeted therapies of chronic myeloid leukemia (CML) using tyrosine kinase inhibitors (TKI)
have profoundly changed the natural history of the disease with a major impact on survival …

Angiogenesis in hematologic malignancies

TM Moehler, AD Ho, H Goldschmidt… - Critical reviews in oncology …, 2003 - Elsevier
Angiogenesis is defined as the formation of new capillaries from preexisting blood vessels
and plays an important role in the progression of solid tumors. Recently a similar …

Tumor origin of endothelial cells in human neuroblastoma

A Pezzolo, F Parodi, MV Corrias, R Cinti… - Journal of Clinical …, 2007 - ascopubs.org
Purpose Malignant cells are genetically unstable and prone to develop chemotherapy
resistance, whereas tumor vasculature is usually of host origin and genetically stable. Tumor …

Role of progenitor endothelial cells in cardiovascular disease and upcoming therapies

A Kawamoto, T Asahara - Catheterization and Cardiovascular …, 2007 - Wiley Online Library
The field of cell‐based transplantation has expanded considerably and is poised to become
an established cardiovascular therapy in the near future. In this review, we will focus on …

Elucidating critical mechanisms of deregulated stem cell turnover in the chronic phase of chronic myeloid leukemia

TL Holyoake, X Jiang, MW Drummond, AC Eaves… - Leukemia, 2002 - nature.com
Chronic myeloid leukemia (CML) has been studied intensively for many years; yet its
treatment remains problematic and its biology remains elusive. In chronic phase, the …

Repopulation of liver endothelium by bone-marrow-derived cells

Z Gao, VC McAlister, GM Williams - The Lancet, 2001 - thelancet.com
The mechanism underlying the immunological advantage of hepatic allografts relative to
other organs is incompletely understood. We used molecular probes for the repetitive units …

[HTML][HTML] Contribution of endothelial progenitor cells to neovascularization

DW Li, ZQ Liu, J Wei, Y Liu… - … journal of molecular …, 2012 - spandidos-publications.com
Endothelial progenitor cells (EPCs) are a cell population mobilized from bone marrow into
the peripheral circulation and recruited into sites of vessel injury to participate in blood …

[HTML][HTML] Punish the parent not the progeny

LJ Elrick, HG Jorgensen, JC Mountford, TL Holyoake - Blood, 2005 - Elsevier
Chronic myeloid leukemia (CML) is sustained by a rare population of primitive, quiescent,
BCR-ABL+ cells and represents an excellent example of a malignancy in which tumor …

Tumor exploits alternative strategies to achieve vascularization

B Bussolati, C Grange, G Camussi - The FASEB Journal, 2011 - Wiley Online Library
Neoangiogenesis is crucial for solid tumor growth and invasion, as the vasculature provides
metabolic support and access to the circulation. Current antiangiogenic therapies have been …

Liver sinusoidal endothelial cells are a site of murine cytomegalovirus latency and reactivation

CK Seckert, A Renzaho, HM Tervo, C Krause… - Journal of …, 2009 - Am Soc Microbiol
Latent cytomegalovirus (CMV) is frequently transmitted by organ transplantation, and its
reactivation under conditions of immunosuppressive prophylaxis against graft rejection by …