Oxidative stress and inflammation: elucidating mechanisms of smoking-attributable pathology for therapeutic targeting

TA Addissouky, IET El Sayed, MMA Ali, Y Wang… - Bulletin of the National …, 2024 - Springer
Background Tobacco smoking remains a major preventable cause of disease and death
worldwide. Combustible cigarettes release thousands of chemicals that can initiate …

Emerging advanced approaches for diagnosis and inhibition of liver fibrogenesis

TA Addissouky, MMA Ali, IETE Sayed… - The Egyptian Journal of …, 2024 - Springer
Background Liver fibrosis results from chronic liver injury and is characterized by excessive
deposition of extracellular matrix proteins including collagen. It can progress to cirrhosis and …

[PDF][PDF] Transforming toxicity assessment through microphysiology, bioprinting, and computational modeling

TA Addissouky, Y Wang… - Advances in Clinical …, 2024 - researchgate.net
Background: Traditional toxicity testing emphasizes animal models with growing concerns
regarding predictive capacity, throughput and ethics. Rapid innovation surrounding human …

[PDF][PDF] Regenerating damaged joints: the promise of tissue engineering and nanomedicine in lupus arthritis

TA Addissouky, IET El Sayed… - J Clinical Orthopaedics and …, 2024 - researchgate.net
Background: Lupus osteoarthritis is a disabling complication of systemic lupus
erythematosus (SLE) caused by persistent inflammation and biomechanical factors. The …

[PDF][PDF] Conservative and Emerging Rehabilitative Approaches for Knee Osteoarthritis Management

TA Addissouky, IE El Sayed, MM Ali - J Clinical Orthopaedics and …, 2024 - researchgate.net
Background: Knee osteoarthritis (OA) involves complex interactions between biological and
biomechanical factors that drive joint degeneration. Conservative rehabilitation approaches …

Optical insights into fibrotic livers: Applications of near-infrared spectroscopy and machine learning

TA Addissouky, IET El Sayed, MMA Ali… - Archives of …, 2024 - scientificarchives.com
Background: Liver fibrosis staging is critical for patient selection and management prior to
transplantation, but biopsy is invasive and serum biomarkers lack accuracy. Near-infrared …

[PDF][PDF] Harnessing Technology for Effective Sickle Cell Disease Awareness Among Ugandan Adolescents: A Review

EI Obeagu, O EzeanyaCU - Elite Journal of Public Health, 2023 - academia.edu
Abstract Sickle Cell Disease (SCD) poses a significant health challenge among adolescents
in Uganda, necessitating innovative approaches for awareness and education. This review …

Type 1 diabetes mellitus: retrospect and prospect

TA Addissouky, MMA Ali, IET El Sayed… - Bulletin of the National …, 2024 - Springer
Abstract Background Type 1 diabetes (T1D) is an autoimmune disease leading to
destruction of insulin-producing pancreatic beta cells. Both genetic and environmental …

Realizing the Promise of Artificial Intelligence in Hepatocellular Carcinoma through Opportunities and Recommendations for Responsible Translation

T Addissouky, MMA Ali, IET El Sayed… - Jurnal Online …, 2024 - join.if.uinsgd.ac.id
This study aims to provide an overview of the current state-of-the-art applications of artificial
intelligence (AI) and machine learning in the management of hepatocellular carcinoma …

[HTML][HTML] Machine Learning Approach towards Quality Assurance, Challenges and Possible Strategies in Laboratory Medicine

QU Ain, R Nazir, A Nawaz, H Shahbaz… - Journal of Clinical …, 2024 - xiahepublishing.com
The burgeoning integration of machine learning (ML) and automation in laboratory medicine
marks a significant shift, propelling the sector towards enhanced diagnostic accuracy and …