Female subfertility
Subfertility is common and affects one in six couples, half of whom lack an explanation for
their delay in conceiving. Developments in the diagnosis and treatment of subfertility over …
their delay in conceiving. Developments in the diagnosis and treatment of subfertility over …
[HTML][HTML] Molecular control of rodent spermatogenesis
Spermatogenesis is a complex developmental process that ultimately generates mature
spermatozoa. This process involves a phase of proliferative expansion, meiosis, and …
spermatozoa. This process involves a phase of proliferative expansion, meiosis, and …
[HTML][HTML] Towards a multi-omics of male infertility
AO Wagner, A Turk, T Kunej - The world journal of men's health, 2023 - ncbi.nlm.nih.gov
Infertility is a common problem affecting one in six couples and in 30% of infertile couples,
the male factor is a major cause. A large number of genes are involved in spermatogenesis …
the male factor is a major cause. A large number of genes are involved in spermatogenesis …
Incorrect DNA methylation of the DAZL promoter CpG island associates with defective human sperm
P Navarro-Costa, P Nogueira, M Carvalho… - Human …, 2010 - academic.oup.com
BACKGROUND Successful gametogenesis requires the establishment of an appropriate
epigenetic state in developing germ cells. Nevertheless, an association between abnormal …
epigenetic state in developing germ cells. Nevertheless, an association between abnormal …
Male hypogonadism: an extended classification based on a developmental, endocrine physiology‐based approach
RA Rey, RP Grinspon, S Gottlieb, T Pasqualini… - …, 2013 - Wiley Online Library
Normal testicular physiology results from the integrated function of the tubular and interstitial
compartments. Serum markers of interstitial tissue function are testosterone and insulin‐like …
compartments. Serum markers of interstitial tissue function are testosterone and insulin‐like …
Spermatogonial stem cell autotransplantation and germline genomic editing: a future cure for spermatogenic failure and prevention of transmission of genomic …
CL Mulder, Y Zheng, SZ Jan, RB Struijk… - Human …, 2016 - academic.oup.com
BACKGROUND Subfertility affects approximately 15% of all couples, and a severe male
factor is identified in 17% of these couples. While the etiology of a severe male factor …
factor is identified in 17% of these couples. While the etiology of a severe male factor …
RFX2 is a major transcriptional regulator of spermiogenesis
WS Kistler, D Baas, S Lemeille, M Paschaki… - PLoS …, 2015 - journals.plos.org
Spermatogenesis consists broadly of three phases: proliferation of diploid germ cells,
meiosis, and finally extensive differentiation of the haploid cells into effective delivery …
meiosis, and finally extensive differentiation of the haploid cells into effective delivery …
Genetics of male infertility
JM Hotaling - Urologic Clinics, 2014 - urologic.theclinics.com
Approximately 1 in 6 couples in the Western world is not able to conceive spontaneously
after 1 year of unprotected intercourse; in nearly half of these couples, the male partner has …
after 1 year of unprotected intercourse; in nearly half of these couples, the male partner has …
Altered microRNA profiles of testicular biopsies from patients with nonobstructive azoospermia
HT Zhang, Z Zhang, K Hong, WH Tang… - Asian journal of …, 2020 - journals.lww.com
Many studies have shown that microRNAs (miRNAs) play vital roles during the
spermatogenesis. However, little is known about the altered miRNA profiles of testicular …
spermatogenesis. However, little is known about the altered miRNA profiles of testicular …
Mediterranean diet and the risk of poor semen quality: cross‐sectional analysis of men referring to an Italian Fertility Clinic
E Ricci, F Bravi, S Noli, S Ferrari, V De Cosmi… - …, 2019 - Wiley Online Library
Background Several diet patterns have been suggested as involved in processes of
spermatogenesis and thus in male subfertility. To study the relation between Mediterranean …
spermatogenesis and thus in male subfertility. To study the relation between Mediterranean …