Crosstalk between circRNAs and the PI3K/AKT signaling pathway in cancer progression

C Xue, G Li, J Lu, L Li - Signal transduction and targeted therapy, 2021 - nature.com
Circular RNAs (circRNAs), covalently closed noncoding RNAs, are widely expressed in
eukaryotes and viruses. They can function by regulating target gene expression, linear RNA …

microRNA‐based diagnostic and therapeutic applications in cancer medicine

LF Sempere, AS Azmi, A Moore - Wiley Interdisciplinary …, 2021 - Wiley Online Library
It has been almost two decades since the first link between microRNAs and cancer was
established. In the ensuing years, this abundant class of short noncoding regulatory RNAs …

[PDF][PDF] Determination of effective albumin in patients with decompensated cirrhosis: clinical and prognostic implications

M Baldassarre, M Naldi, G Zaccherini, M Bartoletti… - …, 2021 - Wiley Online Library
Background and Aims Circulating albumin in cirrhosis can be dysfunctional because of
accumulating structural damages, leading to the concept of effective albumin concentration …

DNA Tile and Invading Stacking Primer-Assisted CRISPR–Cas12a Multiple Amplification System for Entropy-Driven Electrochemical Detection of MicroRNA with …

H Wang, YL Li, YJ Fan, JX Dong, X Ren, H Ma… - Analytical …, 2023 - ACS Publications
Conventional electrochemical detection of microRNA (miRNA) encounters issues of poor
sensitivity and fixed dynamic range. Here, we report a DNA tile and invading stacking primer …

A review on the role of mir-16-5p in the carcinogenesis

S Ghafouri-Fard, T Khoshbakht, BM Hussen… - Cancer cell …, 2022 - Springer
Abstract miR-16-5p is microRNA with important roles in the development of diverse
malignancies including neuroblastoma, osteosarcoma, hepatocellular carcinoma, cervical …

Is depression the missing link between inflammatory mediators and cancer?

B Polityńska, O Pokorska, AM Wojtukiewicz… - Pharmacology & …, 2022 - Elsevier
Patients with cancer are at greater risk of developing depression in comparison to the
general population and this is associated with serious adverse effects, such as poorer …

Epigenetic modification mechanisms involved in keloid: current status and prospect

W Lv, Y Ren, K Hou, W Hu, Y Yi, M Xiong, M Wu… - Clinical …, 2020 - Springer
Keloid, a common dermal fibroproliferative disorder, is benign skin tumors characterized by
the aggressive fibroblasts proliferation and excessive accumulation of extracellular matrix …

Hypoxia-inducible factor–1α–dependent induction of miR122 enhances hepatic ischemia tolerance

C Ju, M Wang, E Tak, B Kim… - The Journal of …, 2021 - Am Soc Clin Investig
Hepatic ischemia and reperfusion (IR) injury contributes to the morbidity and mortality
associated with liver transplantation. microRNAs (miRNAs) constitute a family of noncoding …

T‐cell immunoglobulin and mucin domain‐containing protein‐4 is critical for Kupffer cell homeostatic function in the activation and resolution of liver ischemia …

M Ni, J Zhang, R Sosa, H Zhang, H Wang, D Jin… - …, 2021 - Wiley Online Library
Background and Aims Liver ischemia reperfusion injury (IRI) remains an unresolved clinical
problem. This study dissected roles of liver‐resident macrophage Kupffer cells (KCs), with a …

Interplay of hypoxia-inducible factors and oxygen therapy in cardiovascular medicine

Y Liang, W Ruan, Y Jiang, R Smalling, X Yuan… - Nature Reviews …, 2023 - nature.com
Mammals have evolved to adapt to differences in oxygen availability. Although systemic
oxygen homeostasis relies on respiratory and circulatory responses, cellular adaptation to …