Tyrosinase is a multi-copper enzyme which is widely distributed in different organisms and
plays an important role in the melanogenesis and enzymatic browning. Therefore, its …

Skin, our first interface to the external environment, is subjected to oxidative stress caused
by a variety of factors such as solar ultraviolet, infrared and visible light, environmental …

Melanogenesis is a process to synthesize melanin, which is a primary responsible for the
pigmentation of human skin, eye and hair. Although numerous enzymatic catalyzed and …

Melanins are pigment molecules that determine the skin, eye, and hair color of the human
subject to its amount, quality, and distribution. Melanocytes synthesize melanin and provide …

Melanogenesis is the process for the production of melanin, which is the primary cause of
human skin pigmentation. Skin‑whitening agents are commercially available for those who …

Human skin, eye and hair color rely on the production of melanin, depending on its quantity,
quality, and distribution, Melanin plays a monumental role in protecting the skin against the …

Melanogenesis is a biosynthetic pathway for the formation of the pigment melanin in human
skin. A key enzyme, tyrosinase, catalyzes the first and only rate-limiting steps in …

Antioxidants are deemed useful in controlling oxidative stress associated with extrinsic skin
aging and pigmentation disorders. Resveratrol is a polyphenol compound found in many …

Abnormally high production of melanin or melanogenesis in skin melanocytes results in
hyperpigmentation disorders, such as melasma, senile lentigines or freckles. These …

Currently, there are three major assaying methods used to validate in vitro whitening activity
from natural products: methods using mushroom tyrosinase, human tyrosinase, and …