Antimicrobial resistance in ESKAPE pathogens

DMP De Oliveira, BM Forde, TJ Kidd… - Clinical microbiology …, 2020 - Am Soc Microbiol
Antimicrobial-resistant ESKAPE (E nterococcus faecium, S taphylococcus aureus, K
lebsiella pneumoniae, A cinetobacter baumannii, P seudomonas aeruginosa, and E …

[HTML][HTML] How to manage Pseudomonas aeruginosa infections

M Bassetti, A Vena, A Croxatto, E Righi, B Guery - Drugs in context, 2018 - ncbi.nlm.nih.gov
Infections with Pseudomonas aeruginosa have become a real concern in hospital-acquired
infections, especially in critically ill and immunocompromised patients. The major problem …

Pseudomonas aeruginosa reference strains PAO1 and PA14: A genomic, phenotypic, and therapeutic review

A Grace, R Sahu, DR Owen, VA Dennis - Frontiers in Microbiology, 2022 - frontiersin.org
Pseudomonas aeruginosa is a ubiquitous, motile, gram-negative bacterium that has been
recently identified as a multi-drug resistant pathogen in critical need of novel therapeutics. Of …

Lifestyle transitions and adaptive pathogenesis of Pseudomonas aeruginosa

M Valentini, D Gonzalez, DAI Mavridou… - Current opinion in …, 2018 - Elsevier
Highlights•Pseudomonas aeruginosa causes acute and chronic infections in
humans.•Virulence factors are co-regulated with lifestyles.•The Gac/Rsm cascade regulates …

[HTML][HTML] Type 3 secretion system of Pseudomonas aeruginosa

G Horna, J Ruiz - Microbiological Research, 2021 - Elsevier
Pseudomonas aeruginosa is an opportunistic pathogen, mainly affecting severe patients,
such as those in intensive care units (ICUs). High levels of antibiotic resistance and a long …

Regulation of biofilm exopolysaccharide production by cyclic di-guanosine monophosphate

MB Poulin, LL Kuperman - Frontiers in Microbiology, 2021 - frontiersin.org
Many bacterial species in nature possess the ability to transition into a sessile lifestyle and
aggregate into cohesive colonies, known as biofilms. Within a biofilm, bacterial cells are …

Advances in the development of antimicrobial peptides and proteins for inhaled therapy

Y Wang, RYK Chang, WJ Britton, HK Chan - Advanced Drug Delivery …, 2022 - Elsevier
Antimicrobial peptides and proteins (APPs) are becoming increasingly important in targeting
multidrug-resistant (MDR) bacteria. APPs is a rapidly emerging area with novel molecules …

Phylogenomic and comparative genomic analyses of species of the family Pseudomonadaceae: Proposals for the genera Halopseudomonas gen. nov. and Atopomonas gen. nov., merger of the …

B Rudra, RS Gupta - International journal of systematic …, 2021 - microbiologyresearch.org
The evolutionary relationships among species of the family Pseudomonadaceae were
examined based on 255 available genomes representing> 85% of the species from this …

The effect of CFTR modulators on airway infection in cystic fibrosis

C Harvey, S Weldon, S Elborn, DG Downey… - International Journal of …, 2022 - mdpi.com
The advent of Cystic fibrosis transmembrane receptor (CFTR) modulators in 2012 was a
critical event in the history of cystic fibrosis (CF) treatment. Unlike traditional therapies that …

Identification of FDA-Approved Drugs as Antivirulence Agents Targeting the pqs Quorum-Sensing System of Pseudomonas aeruginosa

F D'Angelo, V Baldelli, N Halliday… - Antimicrobial Agents …, 2018 - Am Soc Microbiol
The long-term use of antibiotics has led to the emergence of multidrug-resistant bacteria. A
promising strategy to combat bacterial infections aims at hampering their adaptability to the …