Ectopic expression of a mechanosensitive channel confers spatiotemporal resolution to ultrasound stimulations of neurons for visual restoration
S Cadoni, C Demené, I Alcala, M Provansal… - Nature …, 2023 - nature.com
Remote and precisely controlled activation of the brain is a fundamental challenge in the
development of brain–machine interfaces for neurological treatments. Low-frequency …
development of brain–machine interfaces for neurological treatments. Low-frequency …
Activation of mechanosensitive ion channels by ultrasound
Mechanosensitive channels (MSCs) play an important role in how cells transduce
mechanical stimuli into electrical or chemical signals, which provides an interventional …
mechanical stimuli into electrical or chemical signals, which provides an interventional …
Ultrasonic neuromodulation and sonogenetics: a new era for neural modulation
S Wang, W Meng, Z Ren, B Li, T Zhu, H Chen… - Frontiers in …, 2020 - frontiersin.org
Non-invasive ultrasonic neural modulation (UNM), a non-invasive technique with enhanced
spatial focus compared to conventional electrical neural modulation, has attracted much …
spatial focus compared to conventional electrical neural modulation, has attracted much …
Ultrasonic control of neural activity through activation of the mechanosensitive channel MscL
J Ye, S Tang, L Meng, X Li, X Wen, S Chen, L Niu… - Nano …, 2018 - ACS Publications
Externally controlling the excitation of a neuronal subset through ion channels activation can
modulate the firing pattern of an entire neural circuit in vivo. As nanovalves in the cell …
modulate the firing pattern of an entire neural circuit in vivo. As nanovalves in the cell …
Mechanosensitive channel-based optical membrane tension reporter
Plasma membrane tension functions as a global physical organizer of cellular activities.
Technical limitations of current membrane tension measurement techniques have hampered …
Technical limitations of current membrane tension measurement techniques have hampered …
Sonogenetic control of multiplexed genome regulation and base editing
Manipulating gene expression in the host genome with high precision is crucial for
controlling cellular function and behavior. Here, we present a precise, non-invasive, and …
controlling cellular function and behavior. Here, we present a precise, non-invasive, and …
Vision restoration by optogenetic therapy and developments toward sonogenetic therapy
M Provansal, K Marazova, JA Sahel… - … vision science & …, 2022 - tvst.arvojournals.org
After revolutionizing neuroscience, optogenetic therapy has entered successfully in clinical
trials for restoring vision to blind people with degenerative eye diseases, such as retinitis …
trials for restoring vision to blind people with degenerative eye diseases, such as retinitis …
Wireless Force‐Inducing Neuronal Stimulation Mediated by High Magnetic Moment Microdiscs
Noninvasive manipulation of cell signaling is critical in basic neuroscience research and in
developing therapies for neurological disorders and psychiatric conditions. Here, the …
developing therapies for neurological disorders and psychiatric conditions. Here, the …
Response of heterologously expressed pressure sensor-actuator-modulator macromolecule to external mechanical stress
Cells from different organs in the body experience a range of mechanical and osmotic
pressures that change in various diseases, including neurological, cardiovascular …
pressures that change in various diseases, including neurological, cardiovascular …
Manipulation of new fluorescent magnetic nanoparticles with an electromagnetic needle, allowed determining the viscosity of the cytoplasm of M-HeLa cells
I Ramazanova, M Suslov, G Sibgatullina, K Petrov… - Pharmaceuticals, 2023 - mdpi.com
Magnetic nanoparticles (MNPs) have recently begun to be actively used in biomedicine
applications, for example, for targeted drug delivery, in tissue engineering, and in magnetic …
applications, for example, for targeted drug delivery, in tissue engineering, and in magnetic …