Pendrin is a Cl−/HCO 3− exchanger expressed in type B and non-A, non-B intercalated cells
in the distal nephron, where it facilitates Cl− absorption and is involved in Na+ absorption …

The ability to regulate cell volume is crucial for normal physiology; equally the regulation of
extracellular fluid homeostasis is of great importance. Alteration of normal extracellular fluid …

The transport of chloride and bicarbonate across epithelia controls the pH and volume of the
intracellular and luminal fluids, as well as the systemic pH and vascular volume. The anion …

The central roles of luteinizing hormone (LH), progestin and their receptors for initiating
ovulation have been well established. However, signaling pathways and downstream …

Chloride transport proteins play critical roles in inflammatory airway diseases, contributing to
the detrimental aspects of mucus overproduction, mucus secretion, and airway constriction …

Whooping cough is caused by Bordetella pertussis that releases pertussis toxin (PT) which
comprises enzyme A-subunit PTS1 and binding/transport B-subunit. After receptor-mediated …

Abstract Solute carrier family 26 (SLC26) is a family of functionally diverse anion
transporters found in all kingdoms of life. Anions transported by SLC26 proteins include …

The recent immunological investigations, stemming from the studies performed in the
nineties within the clinical trials of the acellular pertussis vaccines, have highlighted the …

Bordetella pertussis produces several toxins that affect host-pathogen interactions. Of these,
the major toxins that contribute to pertussis infection and disease are pertussis toxin …

Bordetella fimbriae (FIM) are generally considered to function as adhesins despite a lack of
experimental evidence supporting this conclusion for Bordetella pertussis and evidence …