Treatment for liver cancer: From sorafenib to natural products
S Man, C Luo, M Yan, G Zhao, L Ma, W Gao - European journal of …, 2021 - Elsevier
Liver cancer most commonly develops in patients with chronic liver disease, the etiology of
which includes viral hepatitis (B and C), alcohol, obesity, dietary carcinogens, and so forth …
which includes viral hepatitis (B and C), alcohol, obesity, dietary carcinogens, and so forth …
Targeting DNA damage and repair: embracing the pharmacological era for successful cancer therapy
K Aziz, S Nowsheen, G Pantelias, G Iliakis… - Pharmacology & …, 2012 - Elsevier
DNA is under constant assault from genotoxic agents which creates different kinds of DNA
damage. The precise replication of the genome and the continuous surveillance of its …
damage. The precise replication of the genome and the continuous surveillance of its …
Functional crosstalk between AKT/mTOR and Ras/MAPK pathways in hepatocarcinogenesis: implications for the treatment of human liver cancer
C Wang, A Cigliano, S Delogu, J Armbruster… - Cell cycle, 2013 - Taylor & Francis
Hepatocellular carcinoma (HCC) is one of the leading causes of cancer-related death
worldwide, with limited treatment options. AKT/mTOR and Ras/MAPK pathways are …
worldwide, with limited treatment options. AKT/mTOR and Ras/MAPK pathways are …
Adjuvant therapy for hepatocellular carcinoma: Current situation and prospects
Z Wang, G Zhang, J Wu, M Jia - Drug Discoveries & Therapeutics, 2013 - jstage.jst.go.jp
Hepatocellular carcinoma (HCC) is one of the most common malignancies worldwide,
accounting for 90% of primary liver cancers, and its incidence is still increasing. While the …
accounting for 90% of primary liver cancers, and its incidence is still increasing. While the …
Cancer stem cells, microRNAs, and therapeutic strategies including natural products
D Vira, SK Basak, MS Veena, MB Wang… - Cancer and Metastasis …, 2012 - Springer
Embryonic stem cells divide continuously and differentiate into organs through the
expression of specific transcription factors at specific time periods. Differentiated adult stem …
expression of specific transcription factors at specific time periods. Differentiated adult stem …
Andrographolide inhibits tumor angiogenesis via blocking VEGFA/VEGFR2-MAPKs signaling cascade
Traditional medicinal herb Andrographis paniculata is known to possess anti-tumor activity,
and its potential active compound is the diterpenoid lactone andrographolide (ANGL). In this …
and its potential active compound is the diterpenoid lactone andrographolide (ANGL). In this …
Is hepatocellular carcinoma the same disease in children and adults? Comparison of histology, molecular background, and treatment in pediatric and adult patients
VB Weeda, DC Aronson, J Verheij… - Pediatric blood & …, 2019 - Wiley Online Library
Pediatric hepatocellular carcinoma (HCC) is rare, resulting in scattered knowledge of tumor
biology and molecular background. Thus far, the variant in children has been treated as a …
biology and molecular background. Thus far, the variant in children has been treated as a …
Heparin inhibits Hepatocyte Growth Factor induced motility and invasion of hepatocellular carcinoma cells through early growth response protein 1
The Hepatocyte Growth Factor (HGF)/c-Met signaling pathway regulates hepatocyte
proliferation, and pathway aberrations are implicated in the invasive and metastatic …
proliferation, and pathway aberrations are implicated in the invasive and metastatic …
Myeloid-derived suppressor cells in the patients with liver resection for hepatitis B virus-related hepatocellular carcinoma
WC Lee, YC Wang, CH Cheng, TH Wu, CF Lee… - Scientific reports, 2019 - nature.com
Liver resection remains the popular treatment for hepatocellular carcinoma (HCC). The aim
of this study was to explore the alteration of immune cells in HCC patients with liver …
of this study was to explore the alteration of immune cells in HCC patients with liver …
Percutaneous radiofrequency ablation for intermediate-stage hepatocellular carcinoma
K Kariyama, A Wakuta, M Nishimura, M Kishida… - Oncology, 2015 - karger.com
Objectives: Radiofrequency ablation plays a key role in the treatment of early-stage
hepatocellular carcinoma. However, it is not recommended for intermediate-stage …
hepatocellular carcinoma. However, it is not recommended for intermediate-stage …