[HTML][HTML] Malaria vaccines since 2000: progress, priorities, products

PE Duffy, J Patrick Gorres - npj Vaccines, 2020 - nature.com
Malaria vaccine development entered a new era in 2015 when the pre-erythrocytic
Plasmodium falciparum candidate RTS, S was favorably reviewed by the European …

Burden, pathology, and costs of malaria in pregnancy: new developments for an old problem

SJ Rogerson, M Desai, A Mayor, E Sicuri… - The Lancet infectious …, 2018 - thelancet.com
Over the past 10 years, knowledge of the burden, economic costs, and consequences of
malaria in pregnancy has improved, and the prevalence of malaria caused by Plasmodium …

[HTML][HTML] The structural basis for CD36 binding by the malaria parasite

FL Hsieh, L Turner, JR Bolla, CV Robinson… - Nature …, 2016 - nature.com
CD36 is a scavenger receptor involved in fatty acid metabolism, innate immunity and
angiogenesis. It interacts with lipoprotein particles and facilitates uptake of long chain fatty …

New insights into malaria pathogenesis

CA Moxon, MP Gibbins, D McGuinness… - Annual Review of …, 2020 - annualreviews.org
Malaria remains a major public health threat in tropical and subtropical regions across the
world. Even though less than 1% of malaria infections are fatal, this leads to about 430,000 …

Severe malaria: what's new on the pathogenesis front?

SC Wassmer, GER Grau - International journal for parasitology, 2017 - Elsevier
Plasmodium falciparum causes the most severe and fatal form of malaria in humans with
over half a million deaths each year. Cerebral malaria, a complex neurological syndrome of …

Sporozoite immunization: innovative translational science to support the fight against malaria

TL Richie, LWP Church, T Murshedkar… - Expert review of …, 2023 - Taylor & Francis
Introduction Malaria, a devastating febrile illness caused by protozoan parasites, sickened
247,000,000 people in 2021 and killed 619,000, mostly children and pregnant women in …

[HTML][HTML] Structural basis for placental malaria mediated by Plasmodium falciparum VAR2CSA

R Ma, T Lian, R Huang, JP Renn, JD Petersen… - Nature …, 2021 - nature.com
Plasmodium falciparum VAR2CSA binds to chondroitin sulfate A (CSA) on the surface of the
syncytiotrophoblast during placental malaria. This interaction facilitates placental …

[HTML][HTML] Contributions of natural killer cells to the immune response against Plasmodium

KS Burrack, GT Hart, SE Hamilton - Malaria Journal, 2019 - Springer
Natural killer (NK) cells are important innate effector cells that are well described in their
ability to kill virally-infected cells and tumors. However, there is increasing appreciation for …

[HTML][HTML] Evaluation of the Pfs25-IMX313/Matrix-M malaria transmission-blocking candidate vaccine in endemic settings

C Mulamba, C Williams, K Kreppel, JB Ouedraogo… - Malaria Journal, 2022 - Springer
Malaria control relies heavily on the use of anti-malarial drugs and insecticides against
malaria parasites and mosquito vectors. Drug and insecticide resistance threatens the …

[HTML][HTML] Pregnancy-specific malarial immunity and risk of malaria in pregnancy and adverse birth outcomes: a systematic review

JC Cutts, PA Agius, Z Lin, R Powell, K Moore, B Draper… - BMC medicine, 2020 - Springer
Background In endemic areas, pregnant women are highly susceptible to Plasmodium
falciparum malaria characterized by the accumulation of parasitized red blood cells (pRBC) …