The broadening scope of oral mucositis and oral ulcerative mucosal toxicities of anticancer therapies

S Elad, N Yarom, Y Zadik… - CA: a cancer journal …, 2022 - Wiley Online Library
Oral mucositis (OM) is a common, highly symptomatic complication of cancer therapy that
affects patients' function, quality of life, and ability to tolerate treatment. In certain patients …

Radiation-induced oral mucositis

OM Maria, N Eliopoulos, T Muanza - Frontiers in oncology, 2017 - frontiersin.org
Radiation-induced oral mucositis (RIOM) is a major dose-limiting toxicity in head and neck
cancer patients. It is a normal tissue injury caused by radiation/radiotherapy (RT), which has …

Head and neck cancers, version 2.2020, NCCN clinical practice guidelines in oncology

DG Pfister, S Spencer, D Adelstein, D Adkins… - Journal of the National …, 2020 - jnccn.org
Treatment is complex for patients with head and neck (H&N) cancers with specific site of
disease, stage, and pathologic findings guiding treatment decision-making. Treatment …

New frontiers in the pathobiology and treatment of cancer regimen-related mucosal injury

M Cinausero, G Aprile, P Ermacora, D Basile… - Frontiers in …, 2017 - frontiersin.org
Mucositis is a common complication of chemotherapy, radiotherapy and targeted agents. It
often affects compliance to anticancer therapies as it frequently causes schedule delays …

Oral mucosal changes induced by anticancer targeted therapies and immune checkpoint inhibitors

E Vigarios, JB Epstein, V Sibaud - Supportive Care in Cancer, 2017 - Springer
Abstract Development of biological targeted therapies and immune checkpoint inhibitors has
redefined the treatment for many cancers; however, the increasing use of new protocols has …

Gingival mesenchymal stem/progenitor cells: a unique tissue engineering gem

KM Fawzy El-Sayed, CE Dörfer - Stem cells international, 2016 - Wiley Online Library
The human gingiva, characterized by its outstanding scarless wound healing properties, is a
unique tissue and a pivotal component of the periodontal apparatus, investing and …

Mucosal injury during anti-cancer treatment: from pathobiology to bedside

D Basile, P Di Nardo, C Corvaja, SK Garattini… - Cancers, 2019 - mdpi.com
Mucositis is one of the most common debilitating side effects related to chemotherapy (CT),
radiation therapy (RT), targeted agents and immunotherapy. It is a complex process …

Oral mucositis in head and neck cancer: Evidence-based management and review of clinical trial data

A Blakaj, M Bonomi, ME Gamez, DM Blakaj - Oral oncology, 2019 - Elsevier
Oral Mucositis (OM) continues to be an oncologic challenge in the context of antineoplastic
therapy for head and neck cancer (HNC) treatment. It is a dose-limiting toxicity of …

Bacterial pneumonia in patients with cancer: novel risk factors and management

JL Wong, SE Evans - Clinics in chest medicine, 2017 - chestmed.theclinics.com
Bacterial pneumonias cause disproportionate morbidity and mortality in patients with cancer,
despite the current aggressive use of prophylactic antibiotics and environmental hygiene …

Oral mucositis on a chip: Modeling induction by chemo-and radiation treatments and recovery

KL Ly, X Luo, CB Raub - Biofabrication, 2022 - iopscience.iop.org
Oral mucositis (OM) is a debilitating complication affecting roughly 70% of head and neck
cancer patients receiving chemotherapy and/or radiation treatment. No broadly effective …