[HTML][HTML] Fibrous Remodeling in Eosinophilic Esophagitis: Clinical Facts and Pathophysiological Uncertainties

L Arias-González, L Rodríguez-Alcolado… - International Journal of …, 2024 - mdpi.com
Eosinophilic esophagitis (EoE) is a chronic, progressive, type 2 inflammatory disease with
increasing global prevalence. An eosinophil-predominant inflammation that permeates the …

[HTML][HTML] Vitamin D and allergic diseases

P Zhang, Q Xu, R Zhu - Frontiers in immunology, 2024 - frontiersin.org
In recent years, the relationship between vitamin D and allergic diseases has received
widespread attention. As a fat-soluble vitamin, vitamin D plays a crucial role in regulating the …

Manipulating immune activity of macrophages: a materials and mechanics perspective

AJ Clevenger, A Jha, E Moore, SA Raghavan - Trends in Biotechnology, 2024 - cell.com
Macrophage immune cells exist on a plastic spectrum of phenotypes governed by their
physical and biochemical environment. Controlling macrophage function to facilitate …

[HTML][HTML] Atherosis-associated lnc_000048 activates PKR to enhance STAT1-mediated polarization of THP-1 macrophages to M1 phenotype

Y Ding, Y Sun, H Wang, H Zhao, R Yin… - Neural Regeneration …, 2024 - journals.lww.com
Our previous study has demonstrated that lnc_000048 is upregulated in large-artery
atherosclerotic stroke and promotes atherosclerosis in ApoE–/–mice. However, little is …

Secreted PTEN binds PLXDC2 on macrophages to drive antitumor immunity and tumor suppression

C Zhang, HM Ma, S Wu, JM Shen, N Zhang, YL Xu… - Developmental Cell, 2024 - cell.com
Loss of phosphatase and tensin homolog (PTEN) has been linked to an immunosuppressive
tumor microenvironment, but its underlying mechanisms remain largely enigmatic. Here, we …

[HTML][HTML] The role of macrophages in rosacea: implications for targeted therapies

Y Liu, Y Zhou, C Chu, X Jiang - Frontiers in Immunology, 2023 - frontiersin.org
Introduction Rosacea, a widespread chronic skin condition, may be influenced by
macrophages, key immune cells in the skin, although their exact role is not yet fully …

MCP-1 and IL-4 encapsulated hydrogel particles with macrophages enrichment and polarization capabilities for systemic lupus erythematosus treatment

S Zhu, D Huang, Q Luan, Y Li, J Gan, Y Zhao, L Sun - Nano Research, 2024 - Springer
Macrophages play a pivotal role in systemic lupus erythematosus (SLE) therapy. Efforts
have been made to develop multifunctional drug delivery systems capable of directing …

Research progress on the role of macrophages in acne and regulation by natural plant products

D Zhao, Y Wang, S Wu, X Ji, K Gong, H Zheng… - Frontiers in …, 2024 - frontiersin.org
Acne vulgaris is one of the most common skin diseases. The current understanding of acne
primarily revolves around inflammatory responses, sebum metabolism disorders, aberrant …

Macrophage Functions in Psoriasis: Lessons from Mouse Models

K Nazimek, K Bryniarski - International Journal of Molecular Sciences, 2024 - mdpi.com
Psoriasis is a systemic autoimmune/autoinflammatory disease that can be well studied in
established mouse models. Skin-resident macrophages are classified into epidermal …

[HTML][HTML] Cayratia albifolia CLLi exerts anti-rheumatoid arthritis effect by inhibiting macrophage activation and neutrophil extracellular traps (NETs)

W Wang, ZQ Zhang, YC Zhang, YQ Wu, Z Yang… - Chinese Medicine, 2024 - Springer
Abstract Background Cayratia albifolia CL Li (CAC), commonly known as “Jiao-Mei-Gu” in
China, has been extensively utilized by the Dong minority for several millennia to effectively …