Treatment of pulmonary arterial hypertension: recent progress and a look to the future

M Humbert, O Sitbon, C Guignabert… - The Lancet …, 2023 - thelancet.com
Pulmonary arterial hypertension (PAH) is a severe but treatable form of pre-capillary
pulmonary hypertension caused by pulmonary vascular remodelling. As a result of basic …

Severe Pulmonary Hypertension in Pulmonary Alveolar Microlithiasis: A Comprehensive Literature Review

G Cueto-Robledo, LM Gonzalez-Hermosillo… - Current Problems in …, 2024 - Elsevier
This review focuses on Pulmonary Alveolar Microlithiasis (PAM), an autosomal recessive
genetic disorder characterized by calcium crystal deposits (microliths) resulting from loss of …

Forsythoside B Mitigates Monocrotaline-Induced Pulmonary Arterial Hypertension via Blocking the NF-κB Signaling Pathway to Attenuate Vascular Remodeling

J Liu, G Fang, C Lan, C Qiu, L Yao… - Drug Design …, 2024 - Taylor & Francis
Purpose Pulmonary arterial hypertension (PAH) is a devastating disease with little effective
treatment. The proliferation of pulmonary artery smooth muscle cells (PASMCs) induced by …

[HTML][HTML] A peripheral system disease—Pulmonary hypertension

Y Sun, C Chen, Q Yan, S Wang, Y Tan, J Long… - Biomedicine & …, 2024 - Elsevier
Pulmonary hypertension (PH) is a cardiovascular disorder characterized by substantial
morbidity and mortality rates. It is a chronic condition characterized by intricate pathogenesis …

[HTML][HTML] miR-135b: an emerging player in cardio-cerebrovascular diseases

Y Shao, J Xu, W Chen, M Hao, X Liu, R Zhang… - Journal of …, 2024 - Elsevier
Abstract miR-135 is a highly conserved miRNA in mammals and includes miR-135a and
miR-135b. Recent studies have shown that miR-135b is a key regulatory factor in cardio …

SGLT2 inhibitors as a potential therapeutic option for pulmonary hypertension: mechanisms and clinical perspectives

JS Tan, Y Wei, L Chong, Y Yang, S Hu… - Critical Reviews in …, 2024 - Taylor & Francis
Pulmonary arterial hypertension (PAH), one subtype of pulmonary hypertension (PH), is a
life-threatening condition characterized by pulmonary arterial remodeling, elevated …

Illuminating the many faces of pulmonary hypertension

J Newman, J Pepke-Zaba - The Lancet Respiratory Medicine, 2023 - thelancet.com
The field of pulmonary hypertension has been transformed beyond recognition over the past
30 years. Advances in the understanding of pathophysiology has led to the testing of …

[HTML][HTML] Noncoding RNAs in Chronic Obstructive Pulmonary Disease: From Pathogenesis to Therapeutic Targets

B Ren, H Su, C Bao, H Xu, Y Xiao - Non-coding RNA Research, 2024 - Elsevier
Chronic obstructive pulmonary disease (COPD) is the most prevalent chronic respiratory
disorder that is becoming the leading cause of morbidity and mortality on a global scale …

Expiratory Venous Volume and Arterial Tortuosity are Associated with Disease Severity and Mortality Risk in Patients with COPD: Results from COSYCONET

MG Stoleriu, M Pienn, RA Joerres, P Alter… - … Journal of Chronic …, 2024 - Taylor & Francis
Purpose The aim of this study was to evaluate the association between computed
tomography (CT) quantitative pulmonary vessel morphology and lung function, disease …

Cardiovascular disease and risk in COPD: a state of the art review

R Polman, JR Hurst, OF Uysal, S Mandal… - Expert review of …, 2024 - Taylor & Francis
ABSTRACT Introduction Chronic Obstructive Pulmonary Disease (COPD) and
cardiovascular diseases (CVD) commonly co-exist. Outcomes of people living with both …