[HTML][HTML] The RNA helicase DDX3 and its role in c-MYC driven germinal center-derived B-cell lymphoma
M Lacroix, H Beauchemin, C Khandanpour… - Frontiers in …, 2023 - frontiersin.org
DDX3X is an RNA helicase with many functions in RNA metabolism such as mRNA
translation, alternative pre-mRNA splicing and mRNA stability, but also plays a role as a …
translation, alternative pre-mRNA splicing and mRNA stability, but also plays a role as a …
[HTML][HTML] Lessons from Using Genetically Engineered Mouse Models of MYC-Induced Lymphoma
R Winkler, EM Piskor, C Kosan - Cells, 2022 - mdpi.com
Oncogenic overexpression of MYC leads to the fatal deregulation of signaling pathways,
cellular metabolism, and cell growth. MYC rearrangements are found frequently among non …
cellular metabolism, and cell growth. MYC rearrangements are found frequently among non …
[HTML][HTML] DDX3: a relevant therapeutic target for lymphoma?
M Lacroix, H Beauchemin, T Möröy - Expert Opinion on …, 2022 - Taylor & Francis
DDX3X is an RNA-helicase that unwinds RNA complexes and regulates mRNA translation
[1]. The DDX3X protein is highly conserved between mice and humans (98%) and contains …
[1]. The DDX3X protein is highly conserved between mice and humans (98%) and contains …
[HTML][HTML] The variant landscape and function of DDX3X in cancer and neurodevelopmental disorders
M Gadek, EH Sherr, SN Floor - Trends in molecular medicine, 2023 - cell.com
RNA molecules rely on proteins across their life cycle. DDX3X encodes an X-linked DEAD-
box RNA helicase with a Y-linked paralog, DDX3Y. DDX3X is central to the RNA life cycle …
box RNA helicase with a Y-linked paralog, DDX3Y. DDX3X is central to the RNA life cycle …
PriOmics: integration of high-throughput proteomic data with complementary omics layers using mixed graphical modeling with group priors
Mass spectrometry (MS)-based high-throughput proteomics data cover abundances of 1,000
s of proteins and facilitate the study of co-and post-translational modifications (CTMs/PTMs) …
s of proteins and facilitate the study of co-and post-translational modifications (CTMs/PTMs) …
Characteristics and prognosis of rrDLBCL with TP53 mutations and a high‐risk subgroup represented by the co‐mutations of DDX3X‐TP53
F Gao, K Hu, P Zheng, H Shi, X Ke - Cancer Medicine, 2023 - Wiley Online Library
Background TP53 mutations have a prognostic significance in relapsed and refractory
diffuse large B‐cell lymphoma (rrDLBCL) patients, and their treatment still faces a great …
diffuse large B‐cell lymphoma (rrDLBCL) patients, and their treatment still faces a great …
RNA binding proteins in cardiovascular development and disease.
SK Verma, MN Kuyumcu-Martinez - Current Topics in …, 2024 - europepmc.org
Congenital heart disease (CHD) is the most common birth defect affecting> 1.35 million
newborn babies worldwide. CHD can lead to prenatal, neonatal, postnatal lethality or life …
newborn babies worldwide. CHD can lead to prenatal, neonatal, postnatal lethality or life …
Genetic Subclones Identify Phenotypic Variation in Diffuse Large B-Cell Lymphoma
B Wang - 2023 - repository.cam.ac.uk
Diffuse large B cell lymphoma (DLBCL) is the most common form of non-Hodgkin's
lymphoma. Many efforts have characterised DLBCL subtypes that account for some of the …
lymphoma. Many efforts have characterised DLBCL subtypes that account for some of the …