Obesity-related metabolic organ inflammation contributes to cardiometabolic disorders. In
obese individuals, changes in lipid fluxes and storage elicit immune responses in the …

Obesity is becoming an epidemic in the United States and worldwide and increases risk for
many diseases, particularly insulin resistance, type 2 diabetes mellitus, and cardiovascular …

Obesity is one of the major health burdens of the 21st century as it contributes to the growing
prevalence of its related comorbidities, including insulin resistance and type 2 diabetes …

Obesity usually is accompanied by inflammation of fat tissue, with a prominent role of
visceral fat. Chronic inflammation in obese fat tissue is of a lower grade than acute immune …

The 1921 discovery of insulin was a Big Bang from which a vast and expanding universe of
research into insulin action and resistance has issued. In the intervening century, some …

Most older individuals develop inflammageing, a condition characterized by elevated levels
of blood inflammatory markers that carries high susceptibility to chronic morbidity, disability …

Obesity is the most common cause of insulin resistance, and the current obesity epidemic is
driving a parallel rise in the incidence of T2DM. It is now widely recognized that chronic …

Obesity is a global epidemic representing a serious public health burden as it is a major risk
factor for the development of cardiovascular disease, stroke and all-cause mortality. Chronic …

The worldwide obesity epidemic has emerged as a major cause of insulin resistance and
Type 2 diabetes. Chronic tissue inflammation is a well-recognized feature of obesity, and the …

Resistance to insulin is a pathophysiological state related to the decreased response of
peripheral tissues to the insulin action, hyperinsulinemia and raised blood glucose levels …