Idiopathic pulmonary fibrosis: an update

P Spagnolo, N Sverzellati, G Rossi, A Cavazza… - Annals of …, 2015 - Taylor & Francis
Idiopathic pulmonary fibrosis (IPF) is the most common and lethal form of idiopathic
interstitial pneumonia. The disease, which occurs primarily in middle-aged and older adults …

[HTML][HTML] Idiopathic pulmonary fibrosis: epidemiology, natural history, phenotypes

J Sauleda, B Núñez, E Sala, JB Soriano - Medical Sciences, 2018 - mdpi.com
Idiopathic pulmonary fibrosis (IPF) is the most common of the idiopathic interstitial
pneumonias. It is characterized by a chronic, progressive, fibrotic interstitial lung disease of …

Lung transplantation in telomerase mutation carriers with pulmonary fibrosis

LL Silhan, PD Shah, DC Chambers… - European …, 2014 - Eur Respiratory Soc
Lung transplantation is the only intervention that prolongs survival in idiopathic pulmonary
fibrosis (IPF). Telomerase mutations are the most common identifiable genetic cause of IPF …

Proteomic biomarkers of survival in idiopathic pulmonary fibrosis

JM Oldham, Y Huang, S Bose, SF Ma… - American Journal of …, 2024 - atsjournals.org
Rationale: Idiopathic pulmonary fibrosis (IPF) causes progressive lung scarring and high
mortality. Reliable and accurate prognostic biomarkers are urgently needed. Objectives: To …

[HTML][HTML] Machine learning identifies signatures of macrophage reactivity and tolerance that predict disease outcomes

P Ghosh, S Sinha, GD Katkar, D Vo, S Taheri… - …, 2023 - thelancet.com
Background Single-cell transcriptomic studies have greatly improved organ-specific insights
into macrophage polarization states are essential for the initiation and resolution of …

Lung transplant outcomes in patients with pulmonary fibrosis with telomere-related gene variants

AC Swaminathan, ML Neely, CW Frankel, FL Kelly… - Chest, 2019 - Elsevier
Background Pulmonary fibrosis (PF) is the most common disease indication for lung
transplantation. Our recent work implicated an excess of rare genetic variants in the …

Update on therapeutic management of idiopathic pulmonary fibrosis

A Tzouvelekis, F Bonella… - Therapeutics and clinical …, 2015 - Taylor & Francis
Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive diffuse parenchymal lung
disease of unknown origin, with a mortality rate exceeding that of many cancers. The …

Normativa sobre el diagnóstico y tratamiento de la fibrosis pulmonar idiopática

A Xaubet, J Ancochea, E Bollo… - Archivos de …, 2013 - Elsevier
La fibrosis pulmonar idiopática se define como una neumonía intersticial fibrosante crónica,
limitada al pulmón, de causa desconocida, con mal pronóstico y escasas opciones …

[HTML][HTML] Protective effects of Rosavin on bleomycin-induced pulmonary fibrosis via suppressing fibrotic and inflammatory signaling pathways in mice

X Xin, D Yao, K Zhang, S Han, D Liu, H Wang… - Biomedicine & …, 2019 - Elsevier
Idiopathic Pulmonary fibrosis (IPF) is diagnosed as a life-threatening, progressive and
incurable lung disease characterized by accumulation of extracellular matrix and …

Targeting sphingosine-1-phosphate signaling in lung diseases

DL Ebenezer, P Fu, V Natarajan - Pharmacology & therapeutics, 2016 - Elsevier
Abstract Sphingosine-1-phosphate (S1P), a simple, bioactive sphingolipid metabolite, plays
a key role, both intracellularly and extracellularly, in various cellular processes such as …