Perfusion and endothelialization of engineered tissues with patterned vascular networks

IS Kinstlinger, GA Calderon, MK Royse, AK Means… - Nature …, 2021 - nature.com
As engineered tissues progress toward therapeutically relevant length scales and cell
densities, it is critical to deliver oxygen and nutrients throughout the tissue volume via …

[HTML][HTML] Scaffold guided bone regeneration for the treatment of large segmental defects in long bones

F Schulze, A Lang, J Schoon, GI Wassilew, J Reichert - Biomedicines, 2023 - mdpi.com
Bone generally displays a high intrinsic capacity to regenerate. Nonetheless, large osseous
defects sometimes fail to heal. The treatment of such large segmental defects still represents …

[HTML][HTML] Biophysical stimuli as the fourth pillar of bone tissue engineering

Z Hao, Z Xu, X Wang, Y Wang, H Li, T Chen… - Frontiers in Cell and …, 2021 - frontiersin.org
The repair of critical bone defects remains challenging worldwide. Three canonical pillars
(biomaterial scaffolds, bioactive molecules, and stem cells) of bone tissue engineering have …

3D bioprinting optimization of human mesenchymal stromal cell laden gelatin-alginate-collagen bioink

SW Sawyer, K Takeda, A Alayoubi… - Biomedical …, 2022 - iopscience.iop.org
Abstract 3D bioprinting technology has gained increased attention in the regenerative
medicine and tissue engineering communities over the past decade with their attempts to …

Droplet bioprinting of acellular and cell-laden structures at high-resolutions

P Kunwar, U Aryal, A Poudel, D Fougnier… - …, 2024 - iopscience.iop.org
Advances in digital light projection (DLP) based (bio) printers have made printing of intricate
structures at high resolution possible using a wide range of photosensitive bioinks. A typical …

Investigation of osteogenesis and angiogenesis in perfusion bioreactors using improved multi-layer PCL-nHA-nZnO electrospun scaffolds

SM Deymeh, S Hashemi-Najafabadi… - Biotechnology …, 2023 - Springer
Purpose Bone tissue engineering aims to create a three-dimensional, matured, angiogenic
scaffold with a suitable thickness that resembles a natural bone matrix. On the other hand …

[PDF][PDF] Scaffold Guided Bone Regeneration for the Treatment of Large Segmental Defects in Long Bones. Biomedicines 2023, 11, 325

F Schulze, A Lang, J Schoon, GI Wassilew, J Reichert - 2023 - researchgate.net
Bone generally displays a high intrinsic capacity to regenerate. Nonetheless, large osseous
defects sometimes fail to heal. The treatment of such large segmental defects still represents …

In vitro model to study confined osteocyte networks exposed to flow-induced mechanical stimuli

K Zhang, C Ogando, A Filip, T Zhang… - Biomedical …, 2022 - iopscience.iop.org
Osteocytes are considered the primary mechanical sensor in bone tissue and orchestrate
the coupled bone remodeling activity of adjacent osteoblast and osteoclast cells. In vivo …

Engineered Tissues Supported by Convection and Diffusion through Dendritic Vascular Networks

IS Kinstlinger - 2020 - search.proquest.com
Metabolic function in mammalian tissues is sustained by the delivery of oxygen and nutrients
as well as the removal of waste through complex, three-dimensional (3D) networks of …