Background: Clinimetrics was introduced three decades ago to specify the domain of clinical
markers in clinical medicine (indexes or rating scales). In this perspective, clinical validity is …

Abstract Introduction: Patient-reported outcomes (PROs) are of increasing importance in
clinical medicine. However, their evaluation by classic psychometric methods carries …

• The comparative efficacy of propranolol and amitriptyline in the prophylaxis of migraine
headache was studied in 30 patients in a double-blind, placebocontrolled, crossover design …

Two self-rating scales of psychological distress, the Symptom Rating Test (SRT) and the
Symptom Questionnaire (SQ), have been validated in translations in Italy. They were …

• We administered two validated scales of hypochondriacal concerns (the Illness Behavior
Questionnaire and the Illness Attitude Scales) to 60 medical students and matched law …

• In a double-blind crossover study the β-adrenergic blocking drug propranolol
hydrochloride reduced symptoms in 17 of 26 patients with chronic anxiety disorders. Both …

Studies evaluating the antianxiety and antipanic properties of β-blockers do not support their
routine use in treating either generalized anxiety disorder or panic disorder. The use of …

In order to examine the relationship of dyspnea to anxiety and depression, the authors rated
dyspnea using several methods in 50 patients with chronic respiratory impairment. Anxiety …

Three instruments for the assessment of quality of life, the Quality of Well Being index
(QWB), the Nottingham Health Profile (NHP) and the Sickness Impact Profile (SIP) were …

Different methods of assessing depression and anxiety were tested in 20 patients suffering
from a major depressive disorder with melancholia and 20 matched control subjects …