[HTML][HTML] Pulmonary delivery of siRNA against acute lung injury/acute respiratory distress syndrome

M Zoulikha, Q Xiao, GF Boafo, MA Sallam… - … Pharmaceutica Sinica B, 2022 - Elsevier
The use of small interfering RNAs (siRNAs) has been under investigation for the treatment of
several unmet medical needs, including acute lung injury/acute respiratory distress …

A review on analysis methods, source identification, and cancer risk evaluation of atmospheric polycyclic aromatic hydrocarbons

L Famiyeh, K Chen, J Xu, Y Sun, Q Guo, C Wang… - Science of the Total …, 2021 - Elsevier
Polycyclic aromatic hydrocarbons (PAHs) have gained attention because of their
environmental persistence and effects on ecosystems, animals, and human health. They are …

Advances and future perspectives in epithelial drug delivery

Y Mohammed, A Holmes, PCL Kwok, T Kumeria… - Advanced Drug Delivery …, 2022 - Elsevier
Epithelial surfaces protect exposed tissues in the body against intrusion of foreign materials,
including xenobiotics, pollen and microbiota. The relative permeability of the various …

Regional and disease specific human lung extracellular matrix composition

ET Hoffman, FE Uhl, L Asarian, B Deng, C Becker… - Biomaterials, 2023 - Elsevier
Chronic lung diseases, such as chronic obstructive pulmonary disease (COPD) and
idiopathic pulmonary fibrosis (IPF), are characterized by regional extracellular matrix (ECM) …

Respirable coal mine dust: a review of respiratory deposition, regulations, and characterization

Y Shekarian, E Rahimi, M Rezaee, WC Su… - Minerals, 2021 - mdpi.com
In the late 1990s, despite years of efforts to understand and reduce coal worker's
pneumoconiosis (CWP) prevalence from more than 30% in 1970 to less than 4.2%, the level …

Role of CFD based in silico modelling in establishing an in vitro-in vivo correlation of aerosol deposition in the respiratory tract

F Huang, Q Zhu, X Zhou, D Gou, J Yu, R Li… - Advanced drug delivery …, 2021 - Elsevier
Effective evaluation and prediction of aerosol transport deposition in the human respiratory
tracts are critical to aerosol drug delivery and evaluation of inhalation products …

How microplastics are transported and deposited in realistic upper airways?

MS Islam, MM Rahman, P Larpruenrudee… - Physics of …, 2023 - pubs.aip.org
Microplastics are tiny plastic debris in the environment from industrial processes, various
consumer items, and the breakdown of industrial waste. Recently, microplastics have been …

Flow structure and particle deposition analyses for optimization of a pressurized metered dose inhaler (pMDI) in a model of tracheobronchial airway

K Ahookhosh, M Saidi, M Mohammadpourfard… - European Journal of …, 2021 - Elsevier
Inhalation therapy plays an important role in management or treatment of respiratory
diseases such asthma and chronic obstructive pulmonary diseases (COPDs). For decades …

Gelation of Uniform Interfacial Diffusant in Embedded 3D Printing

S Shin, LG Brunel, B Cai, D Kilian… - Advanced Functional …, 2023 - Wiley Online Library
While the human body has many different examples of perfusable structures with complex
geometries, biofabrication methods to replicate this complexity are still lacking. Specifically …

In silico evaluation of particle transport and deposition in the airways of individual patients with chronic obstructive pulmonary disease

K Kadota, K Matsumoto, H Uchiyama, S Tobita… - European Journal of …, 2022 - Elsevier
Inhalation therapy can effectively treat chronic obstructive pulmonary disease (COPD), but
the physical factors determining the appropriate aerosol delivery into the targeted airways …