[HTML][HTML] Pulmonary delivery of siRNA against acute lung injury/acute respiratory distress syndrome
M Zoulikha, Q Xiao, GF Boafo, MA Sallam… - … Pharmaceutica Sinica B, 2022 - Elsevier
The use of small interfering RNAs (siRNAs) has been under investigation for the treatment of
several unmet medical needs, including acute lung injury/acute respiratory distress …
several unmet medical needs, including acute lung injury/acute respiratory distress …
A review on analysis methods, source identification, and cancer risk evaluation of atmospheric polycyclic aromatic hydrocarbons
Polycyclic aromatic hydrocarbons (PAHs) have gained attention because of their
environmental persistence and effects on ecosystems, animals, and human health. They are …
environmental persistence and effects on ecosystems, animals, and human health. They are …
Advances and future perspectives in epithelial drug delivery
Epithelial surfaces protect exposed tissues in the body against intrusion of foreign materials,
including xenobiotics, pollen and microbiota. The relative permeability of the various …
including xenobiotics, pollen and microbiota. The relative permeability of the various …
Regional and disease specific human lung extracellular matrix composition
ET Hoffman, FE Uhl, L Asarian, B Deng, C Becker… - Biomaterials, 2023 - Elsevier
Chronic lung diseases, such as chronic obstructive pulmonary disease (COPD) and
idiopathic pulmonary fibrosis (IPF), are characterized by regional extracellular matrix (ECM) …
idiopathic pulmonary fibrosis (IPF), are characterized by regional extracellular matrix (ECM) …
Respirable coal mine dust: a review of respiratory deposition, regulations, and characterization
In the late 1990s, despite years of efforts to understand and reduce coal worker's
pneumoconiosis (CWP) prevalence from more than 30% in 1970 to less than 4.2%, the level …
pneumoconiosis (CWP) prevalence from more than 30% in 1970 to less than 4.2%, the level …
Role of CFD based in silico modelling in establishing an in vitro-in vivo correlation of aerosol deposition in the respiratory tract
F Huang, Q Zhu, X Zhou, D Gou, J Yu, R Li… - Advanced drug delivery …, 2021 - Elsevier
Effective evaluation and prediction of aerosol transport deposition in the human respiratory
tracts are critical to aerosol drug delivery and evaluation of inhalation products …
tracts are critical to aerosol drug delivery and evaluation of inhalation products …
How microplastics are transported and deposited in realistic upper airways?
Microplastics are tiny plastic debris in the environment from industrial processes, various
consumer items, and the breakdown of industrial waste. Recently, microplastics have been …
consumer items, and the breakdown of industrial waste. Recently, microplastics have been …
Flow structure and particle deposition analyses for optimization of a pressurized metered dose inhaler (pMDI) in a model of tracheobronchial airway
K Ahookhosh, M Saidi, M Mohammadpourfard… - European Journal of …, 2021 - Elsevier
Inhalation therapy plays an important role in management or treatment of respiratory
diseases such asthma and chronic obstructive pulmonary diseases (COPDs). For decades …
diseases such asthma and chronic obstructive pulmonary diseases (COPDs). For decades …
Gelation of Uniform Interfacial Diffusant in Embedded 3D Printing
While the human body has many different examples of perfusable structures with complex
geometries, biofabrication methods to replicate this complexity are still lacking. Specifically …
geometries, biofabrication methods to replicate this complexity are still lacking. Specifically …
In silico evaluation of particle transport and deposition in the airways of individual patients with chronic obstructive pulmonary disease
K Kadota, K Matsumoto, H Uchiyama, S Tobita… - European Journal of …, 2022 - Elsevier
Inhalation therapy can effectively treat chronic obstructive pulmonary disease (COPD), but
the physical factors determining the appropriate aerosol delivery into the targeted airways …
the physical factors determining the appropriate aerosol delivery into the targeted airways …