The effects of pH on wound healing, biofilms, and antimicrobial efficacy

SL Percival, S McCarty, JA Hunt… - Wound repair and …, 2014 - Wiley Online Library
It is known that pH has a role to play in wound healing. In particular, pH has been shown to
affect matrix metalloproteinase activity, tissue inhibitors of matrix metalloproteinases activity …

Innovative strategies to overcome biofilm resistance

A Taraszkiewicz, G Fila, M Grinholc… - BioMed research …, 2013 - Wiley Online Library
We review the recent literature concerning the efficiency of antimicrobial photodynamic
inactivation toward various microbial species in planktonic and biofilm cultures. The review …

In vitro antibacterial properties of magnesium metal against Escherichia coli, Pseudomonas aeruginosa and Staphylococcus aureus

DA Robinson, RW Griffith, D Shechtman, RB Evans… - Acta biomaterialia, 2010 - Elsevier
Bacterial infections are a costly sequela in any wound. The corrosion properties of 0.15,
0.30, 0.45 and 0.60 g of Mg metal were determined in Mueller–Hinton broth by serially …

Antimicrobial tolerance and the significance of persister cells in recalcitrant chronic wound biofilms

SL Percival, KE Hill, S Malic… - Wound repair and …, 2011 - Wiley Online Library
The application of antimicrobials in the management of wounds is a complex procedure
requiring appropriate clinical decision making, judgment and a thorough understanding of …

[HTML][HTML] Molecular microbiology: new dimensions for cutaneous biology and wound healing

JM Martin, JM Zenilman, GS Lazarus - Journal of Investigative Dermatology, 2010 - Elsevier
The role of bacteria in the pathogenesis of chronic, nonhealing wounds is unclear. All
wounds are colonized with bacteria, but differentiating colonizers from invading organisms is …

Alternative antibiotics in dentistry: Antimicrobial peptides

A Griffith, A Mateen, K Markowitz, SR Singer, C Cugini… - Pharmaceutics, 2022 - mdpi.com
The rise of antibiotic resistant bacteria due to overuse and misuse of antibiotics in medicine
and dentistry is a growing concern. New approaches are needed to combat antibiotic …

Gel-entrapped Staphylococcus aureus bacteria as models of biofilm infection exhibit growth in dense aggregates, oxygen limitation, antibiotic tolerance, and …

B Pabst, B Pitts, E Lauchnor… - Antimicrobial agents and …, 2016 - Am Soc Microbiol
An experimental model that mimicked the structure and characteristics of in vivo biofilm
infections, such as those occurring in the lung or in dermal wounds where no biomaterial …

Current concepts regarding the effect of wound microbial ecology and biofilms on wound healing

CE Black, JW Costerton - Surgical Clinics, 2010 - surgical.theclinics.com
A biofilm is an aggregation of microbes that manufacture a protective carbohydrate matrix,
which allows them to adhere to each other and to a host wound surface. The matrix shields …

In situ monitoring of antibiotic susceptibility of bacterial biofilms in a microfluidic device

KP Kim, YG Kim, CH Choi, HE Kim, SH Lee… - Lab on a Chip, 2010 - pubs.rsc.org
Antibiotic resistance of biofilms is a growing public health concern due to overuse and
improper use of antibiotics. Thus, determining an effective minimal concentration of …

The antimicrobial efficacy of a silver alginate dressing against a broad spectrum of clinically relevant wound isolates

SL Percival, W Slone, S Linton, T Okel… - International Wound …, 2011 - Wiley Online Library
Wound dressings impregnated with silver have a role to play in aiding to reduce both the
dressing and wound microbial bioburden. It is therefore imperative that antimicrobial wound …