[HTML][HTML] Osteoblast differentiation and signaling: established concepts and emerging topics

M Ponzetti, N Rucci - International journal of molecular sciences, 2021 - mdpi.com
Osteoblasts, the cells that build up our skeleton, are remarkably versatile and important cells
that need tight regulation in all the phases of their differentiation to guarantee proper skeletal …

[HTML][HTML] Adipogenesis, osteogenesis, and chondrogenesis of human mesenchymal stem/stromal cells: a comparative transcriptome approach

AW Robert, BH Marcon, B Dallagiovanna… - Frontiers in cell and …, 2020 - frontiersin.org
Adipogenesis, osteogenesis and chondrogenesis of human mesenchymal stem/stromal
cells (MSC) are complex and highly regulated processes. Over the years, several studies …

[HTML][HTML] Aged bone matrix-derived extracellular vesicles as a messenger for calcification paradox

ZX Wang, ZW Luo, FXZ Li, J Cao, SS Rao… - Nature …, 2022 - nature.com
Adipocyte differentiation of bone marrow mesenchymal stem/stromal cells (BMSCs) instead
of osteoblast formation contributes to age-and menopause-related marrow adiposity and …

Bioactive glass nanoparticles inhibit osteoclast differentiation and osteoporotic bone loss by activating lncRNA NRON expression in the extracellular vesicles derived …

Z Yang, X Liu, F Zhao, M Yao, Z Lin, Z Yang, C Liu… - Biomaterials, 2022 - Elsevier
Bioactive glass nanoparticles (BGN) have attracted increasing attention for their use in bone
tissue repair owing to their special osteogenic activity; however, the underlying molecular …

[HTML][HTML] The role of micro RNA and long-non-coding RNA in osteoporosis

NY Ko, LR Chen, KH Chen - International Journal of Molecular Sciences, 2020 - mdpi.com
Osteoporosis is a major concern worldwide and can be attributed to an imbalance between
osteoblastic bone formation and osteoclastic bone resorption due to the natural aging …

[HTML][HTML] A functional motif of long noncoding RNA Nron against osteoporosis

F Jin, J Li, YB Zhang, X Liu, M Cai, M Liu, M Li… - Nature …, 2021 - nature.com
Long noncoding RNAs are widely implicated in diverse disease processes. Nonetheless,
their regulatory roles in bone resorption are undefined. Here, we identify lncRNA Nron as a …

RANKL-responsive epigenetic mechanism reprograms macrophages into bone-resorbing osteoclasts

S Bae, K Kim, K Kang, H Kim, M Lee, B Oh… - Cellular & Molecular …, 2023 - nature.com
Monocyte/macrophage lineage cells are highly plastic and can differentiate into various cells
under different environmental stimuli. Bone-resorbing osteoclasts are derived from the …

Bioinspired mineral hydrogels as nanocomposite scaffolds for the promotion of osteogenic marker expression and the induction of bone regeneration in osteoporosis

Y Zhao, Z Li, Y Jiang, H Liu, Y Feng, Z Wang, H Liu… - Acta Biomaterialia, 2020 - Elsevier
Osteoporosis is one of the most prevalent age-related diseases worldwide and is
characterized by a systemic deterioration of bone strength (bone mineral density and bone …

[HTML][HTML] Advances in the research of the role of macrophage/microglia polarization-mediated inflammatory response in spinal cord injury

SP Fu, SY Chen, QM Pang, M Zhang, XC Wu… - Frontiers in …, 2022 - frontiersin.org
It is often difficult to regain neurological function following spinal cord injury (SCI).
Neuroinflammation is thought to be responsible for this failure. Regulating the inflammatory …

[HTML][HTML] Role of non-coding RNAs and exosomal non-coding RNAs in retinoblastoma progression

N Ahangar Davoodi, S Najafi… - Frontiers in cell and …, 2022 - frontiersin.org
Retinoblastoma (RB) is a rare aggressive intraocular malignancy of childhood that has the
potential to affect vision, and can even be fatal in some children. While the tumor can be …