[HTML][HTML] Inflammatory markers in dysmenorrhea and therapeutic options

Z Barcikowska, E Rajkowska-Labon… - International journal of …, 2020 - mdpi.com
Dysmenorrhea often significantly reduces the quality of women's life and is still an important
public health problem. Despite numerous studies, the pathomechanism of dysmenorrhea is …

[HTML][HTML] CCL2: An important cytokine in normal and pathological pregnancies: A review

Z Lin, JL Shi, M Chen, ZM Zheng, MQ Li… - Frontiers in …, 2023 - frontiersin.org
CC motif ligand 2 (CCL2), also known as monocytic chemotactic protein 1 (MCP-1), is an
integral chemotactic factor which recruits macrophages for the immune response. Together …

[HTML][HTML] A single-cell atlas of the myometrium in human parturition

R Pique-Regi, R Romero, V Garcia-Flores… - JCI insight, 2022 - ncbi.nlm.nih.gov
Parturition is a well-orchestrated process characterized by increased uterine contractility,
cervical ripening, and activation of the chorioamniotic membranes; yet, the transition from a …

Acupuncture for primary dysmenorrhea: A potential mechanism from an anti‐inflammatory perspective

WY Yu, LX Ma, Z Zhang, JD Mu, TY Sun… - Evidence‐Based …, 2021 - Wiley Online Library
The low adverse effects of acupuncture for primary dysmenorrhea (PD), known as one of the
most commonly reported gynecological debilitating conditions affecting women's overall …

PGE2 vs PGF2α in human parturition

W Li, J Lu, C Zhang, W Wang, H Ying, L Myatt, K Sun - Placenta, 2021 - Elsevier
Abstract Prostaglandin E2 (PGE2) and F2α (PGF2α) are the two most prominent prostanoids
in parturition. They are involved in cervical ripening, membrane rupture, myometrial …

Fatty acid-mediated signaling as a target for developing type 1 diabetes therapies

I Díaz Ludovico, S Sarkar, E Elliott… - Expert Opinion on …, 2023 - Taylor & Francis
ABSTRACT Introduction Type 1 diabetes (T1D) is an autoimmune disease in which pro-
inflammatory and cytotoxic signaling drive the death of the insulin-producing β cells. This …

[HTML][HTML] Inflammation, it's regulation and antiphlogistic effect of the cyanogenic glycoside amygdalin

D Figurová, K Tokárová, H Greifová, N Knížatová… - Molecules, 2021 - mdpi.com
The inflammatory reaction accompanies in part or in full any disease process in the
vascularized metazoan. This complicated reaction is controlled by regulatory mechanisms …

[HTML][HTML] Oxytocin receptor antagonists, atosiban and nolasiban, inhibit prostaglandin F2α-induced contractions and inflammatory responses in human myometrium

SH Kim, L Riaposova, H Ahmed, O Pohl, A Chollet… - Scientific Reports, 2019 - nature.com
Oxytocin receptor antagonists (OTR-A) have been developed as tocolytics for the
management of preterm labour due to the significant role of oxytocin (OT) in the onset of …

Cooperative effects of sequential PGF and IL-1β on IL-6 and COX-2 expression in human myometrial cells

KB Leimert, BSE Verstraeten, A Messer… - Biology of …, 2019 - academic.oup.com
The change from the state of pregnancy to the state of parturition, which we call uterine
transitioning, requires the actions of inflammatory mediators and results in an activated …

[HTML][HTML] Term and preterm birth initiation is associated with the macrophages shifting to M1 polarization in gestational tissues in mice

Y Shan, S Shen, J Long, Z Tang, C Wu, X Ni - Biology, 2022 - mdpi.com
Simple Summary Inflammatory responses are critical in term and preterm labor initiation.
The present study represents the inflammatory states in the mouse models' key tissues …