Mapping and manipulating neural circuits in the fly brain

JH Simpson - Advances in genetics, 2009 - Elsevier
Drosophila is a marvelous system to study the underlying principles that govern how neural
circuits govern behaviors. The scale of the fly brain (∼ 100,000 neurons) and the complexity …

Flower colours along an alpine altitude gradient, seen through the eyes of fly and bee pollinators

SEJ Arnold, V Savolainen, L Chittka - Arthropod-Plant Interactions, 2009 - Springer
Alpine flowers face multiple challenges in terms of abiotic and biotic factors, some of which
may result in selection for certain colours at increasing altitude, in particular the changing …

A class of visual neurons with wide-field properties is required for local motion detection

YE Fisher, JCS Leong, K Sporar, MD Ketkar, DM Gohl… - Current Biology, 2015 - cell.com
Visual motion cues are used by many animals to guide navigation across a wide range of
environments. Long-standing theoretical models have made predictions about the …

Stochasticity and determinism in cell fate decisions

C Zechner, E Nerli, C Norden - Development, 2020 - journals.biologists.com
During development, cells need to make decisions about their fate in order to ensure that the
correct numbers and types of cells are established at the correct time and place in the …

Motion-detecting circuits in flies: coming into view

M Silies, DM Gohl, TR Clandinin - Annual review of …, 2014 - annualreviews.org
Visual motion cues provide animals with critical information about their environment and
guide a diverse array of behaviors. The neural circuits that carry out motion estimation …

Temporal patterning of neural progenitors in Drosophila

X Li, Z Chen, C Desplan - Current topics in developmental biology, 2013 - Elsevier
Drosophila has recently become a powerful model system to understand the mechanisms of
temporal patterning of neural progenitors called neuroblasts (NBs). Two different temporal …

[HTML][HTML] Localized netrins act as positional cues to control layer-specific targeting of photoreceptor axons in Drosophila

K Timofeev, W Joly, D Hadjieconomou, I Salecker - Neuron, 2012 - cell.com
A shared feature of many neural circuits is their organization into synaptic layers. However,
the mechanisms that direct neurites to distinct layers remain poorly understood. We …

Neural specification, targeting, and circuit formation during visual system assembly

J Malin, C Desplan - … of the National Academy of Sciences, 2021 - National Acad Sciences
Like other sensory systems, the visual system is topographically organized: Its sensory
neurons, the photoreceptors, and their targets maintain point-to-point correspondence in …

The EGFR-HER2 module: a stem cell approach to understanding a prime target and driver of solid tumors

MR Schneider, Y Yarden - Oncogene, 2016 - nature.com
The epidermal growth factor receptor (EGFR) and a coreceptor denoted HER2/ERBB2 are
frequently overexpressed or mutated in solid tumors, such as carcinomas and gliomas. In …

Horsefly object-directed polarotaxis is mediated by a stochastically distributed ommatidial subtype in the ventral retina

A Meglič, M Ilić, P Pirih, A Škorjanc… - Proceedings of the …, 2019 - National Acad Sciences
The ventral compound eye of many insects contains polarization-sensitive photoreceptors,
but little is known about how they are integrated into visual functions. In female horseflies …