Recent advances in glycyrrhetinic acid-functionalized biomaterials for liver cancer-targeting therapy
A Speciale, C Muscarà, MS Molonia, M Cristani… - Molecules, 2022 - mdpi.com
Liver cancer is one of the most common causes of cancer mortality worldwide.
Chemotherapy and radiotherapy are the conventional therapies generally employed in …
Chemotherapy and radiotherapy are the conventional therapies generally employed in …
Surface receptor‐mediated targeted drug delivery systems for enhanced cancer treatment: A state‐of‐the‐art review
S Kunjiappan, P Pavadai, S Vellaichamy… - Drug Development …, 2021 - Wiley Online Library
Enhanced cancer treatment remains as one of the focused areas for researchers around the
world. Hence, the progress in this direction will be a challenge and an opportunity in, inter …
world. Hence, the progress in this direction will be a challenge and an opportunity in, inter …
pH-activated nanoplatform for visualized photodynamic and ferroptosis synergistic therapy of tumors
R Sun, W Ma, M Ling, C Tang, M Zhong, J Dai… - Journal of Controlled …, 2022 - Elsevier
To overcome drug resistance and improve precision theranostics for hepatocellular
carcinoma (HCC), a nanoplatform with an “off/on” function for multimodality imaging (near …
carcinoma (HCC), a nanoplatform with an “off/on” function for multimodality imaging (near …
TPGS–galactose-modified polydopamine co-delivery nanoparticles of nitric oxide donor and doxorubicin for targeted chemo–photothermal therapy against drug …
Z Du, Y Mao, P Zhang, J Hu, J Fu… - ACS Applied Materials …, 2021 - ACS Publications
The lack of cancer cell specificity and the occurrence of multidrug resistance (MDR) are two
major obstacles in the treatment of hepatocellular carcinoma (HCC). To tackle these …
major obstacles in the treatment of hepatocellular carcinoma (HCC). To tackle these …
Multifunctional polymeric micelle-based nucleic acid delivery: Current advances and future perspectives
Nucleic acid (NA) therapeutics are a rapidly growing class of biomedicines with the ability to
manipulate gene expression in potent and specific manner, and with the enormous potential …
manipulate gene expression in potent and specific manner, and with the enormous potential …
Recent advances in the design of inorganic and nano-clay particles for the treatment of brain disorders
Inorganic materials, in particular nanoclays and silica nanoparticles, have attracted
enormous attention due to their versatile and tuneable properties, making them ideal …
enormous attention due to their versatile and tuneable properties, making them ideal …
[HTML][HTML] Evaluation of polymer nanoformulations in hepatoma therapy by established rodent models
Q Wang, P Zhang, Z Li, X Feng, C Lv, H Zhang… - Theranostics, 2019 - ncbi.nlm.nih.gov
Hepatoma is one of the most severe malignancies usually with poor prognosis, and many
patients are insensitive to the existing therapeutic agents, including the drugs for …
patients are insensitive to the existing therapeutic agents, including the drugs for …
Evoking and enhancing ferroptosis of cancer stem cells by a liver-targeted and metal-organic framework-based drug delivery system inhibits the growth and lung …
P Zhang, J Fu, J Hu, Q You, X Yao, D Hua, J Yin… - Chemical Engineering …, 2023 - Elsevier
Evoking ferroptosis of cancer cells is a useful strategy to prevent tumor growth and
metastasis. However, intrinsic ferroptosis suppressors glutathione peroxidase 4 (GPX4) and …
metastasis. However, intrinsic ferroptosis suppressors glutathione peroxidase 4 (GPX4) and …
A bifunctional hepatocyte-mitochondrion targeting nanosystem for effective astaxanthin delivery to the liver
Z Hua, X Zhang, Y Chen, R Liu, Y Li, J Li, D Liu, M Tan - Food Chemistry, 2023 - Elsevier
A bifunctional hepatocyte-mitochondrion targeting nanosystem was prepared for astaxanthin
by conjugating lactobionic acid (LA) and triphenylphosphonium-modified 2-hydroxypropyl-β …
by conjugating lactobionic acid (LA) and triphenylphosphonium-modified 2-hydroxypropyl-β …
Hepatic Spheroid Formation on Carbohydrate-Functionalized Supramolecular Hydrogels
J Liu, Y Zhang, K van Dongen, C Kennedy… - …, 2023 - ACS Publications
Two synthetic supramolecular hydrogels, formed from bis-urea amphiphiles containing
lactobionic acid (LBA) and maltobionic acid (MBA) bioactive ligands, are applied as cell …
lactobionic acid (LBA) and maltobionic acid (MBA) bioactive ligands, are applied as cell …