Central nervous system pericytes contribute to health and disease

F Girolamo, M Errede, A Bizzoca, D Virgintino, D Ribatti - Cells, 2022 - mdpi.com
Successful neuroprotection is only possible with contemporary microvascular protection.
The prevention of disease-induced vascular modifications that accelerate brain damage …

Repeated ethanol exposure and withdrawal alters angiotensin‐converting enzyme 2 expression in discrete brain regions: Implications for SARS‐CoV‐2 …

N Balasubramanian, TD James… - Alcohol: Clinical and …, 2023 - Wiley Online Library
Background People with alcohol use disorder (AUD) may be at higher risk for COVID‐19.
Angiotensin‐converting enzyme 2 (ACE2) and transmembrane serine protease 2 …

Astrocytes are a key target for neurotropic viral infection

M Potokar, R Zorec, J Jorgačevski - Cells, 2023 - mdpi.com
Astrocytes are increasingly recognized as important viral host cells in the central nervous
system. These cells can produce relatively high quantities of new virions. In part, this can be …

Neurocircuitry hypothesis and clinical experience in treating neuropsychiatric symptoms of postacute sequelae of severe acute respiratory syndrome coronavirus 2

A Newhouse, MD Kritzer, H Eryilmaz… - Journal of the Academy …, 2022 - Elsevier
Persistent symptoms following COVID-19 infection have been termed postacute sequelae of
severe acute respiratory syndrome coronavirus 2 infection. Many of these symptoms are …

Role of neuroinflammation mediated potential alterations in adult neurogenesis as a factor for neuropsychiatric symptoms in Post-Acute COVID-19 syndrome—A …

J Saikarthik, I Saraswathi, A Alarifi, AA Al-Atram… - PeerJ, 2022 - peerj.com
Persistence of symptoms beyond the initial 3 to 4 weeks after infection is defined as post-
acute COVID-19 syndrome (PACS). A wide range of neuropsychiatric symptoms like anxiety …

A peek into Pandora's box: COVID-19 and neurodegeneration

A Chandra, A Johri - Brain Sciences, 2022 - mdpi.com
Ever since it was first reported in Wuhan, China, the coronavirus-induced disease of 2019
(COVID-19) has become an enigma of sorts with ever expanding reports of direct and …

Interplay between the renin angiotensin system and oxidative stress contributes to alcohol addiction by stimulating dopamine accumulation in the mesolimbic pathway

M Sun, C Wu, L Liu, L Gu, Z Wang, F Xu… - Biochemical Pharmacology, 2023 - Elsevier
The brain renin–angiotensin system (RAS) has recently been implicated in the development
of substance abuse and addiction. However, the integrative roles of the two counter …

Altered Gene Expression Within the Renin–Angiotensin System in Normal Aging and Dementia

HM Tayler, R MacLachlan, Ö Güzel… - The Journals of …, 2024 - academic.oup.com
The renin–angiotensin system (RAS) is dysregulated in Alzheimer's disease (AD). In this
study, we have explored the hypothesis that an age-related imbalance in brain RAS is a …

Molecular mechanisms highlighting the potential role of COVID-19 in the development of neurodegenerative diseases

B Rahmani, E Ghashghayi, M Zendehdel… - Physiology …, 2022 - akjournals.com
Abstract Coronavirus disease 2019 (COVID-19) is a contagious disease caused by severe
acute respiratory syndrome coronavirus 2 (SARS-CoV-2). In addition to the pulmonary …

Cerebral Vasomotor Reactivity in COVID-19: A Narrative Review

Z Ghotbi, M Estakhr, M Hosseini, RB Shahripour - Life, 2023 - mdpi.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) primarily affects the
respiratory system but can also lead to neurological complications. Among COVID-19 …