Pain models in animals have shown low predictivity for analgesic efficacy in humans, and
clinical studies are often very confounded, blurring the evaluation. Human experimental pain …

The review concluded that there was fair evidence that percutaneous adhesiolysis was
effective in relieving low back pain and/or leg pain due to post lumbar surgery syndrome or …

Back pain related to intervertebral disc degeneration is the most common musculoskeletal
problem, with a lifetime prevalence of 82%. The lack of effective treatment for this …

Objective To describe trends in rates of prescribing of high-dose opioid formulations and
variations in opioid product selection across Canada. Design Population-based, cross …

Background This study aimed at describing pain-related health care resource use, direct
costs, and productivity loss among patients suffering from fibromyalgia syndrome (FMS) …

The aim of this study was to examine associations between selected physical functional
limitations related to performing daily activities and psychological distress. We also aimed to …

Abstract Background British Columbia is the epicenter of the current fentanyl-related
overdose crisis in Canada. Our study characterizes prescribing histories of people who had …

Background Chronic pain (CP) is a common symptom in patients with inflammatory bowel
disease. This study aimed to examine its prevalence, severity, clinical associations, and …

Background The clinical knowledge of factors related to the spread of pain on the body has
increased and understanding these factors is essential for effective pain treatment. This …

Objective: The study examined the relationship between functional limitation due to chronic
diseases and absenteeism among full-time workers. The studied chronic diseases include …