Primary ovarian insufficiency (POI) is determined by exhaustion of follicles in the ovaries,
which leads to infertility before the age of 40 years. It is characterized by a strong familial …

Ovarian reserve is essential for fertility and influences healthy aging in women. Advanced
maternal age correlates with the progressive loss of both the quantity and quality of oocytes …

Primary ovarian insufficiency (POI) is characterized by amenorrhea, increased follicle-
stimulating hormone (FSH) levels, and hypoestrogenism, leading to infertility before the age …

STUDY QUESTION Is it possible to find the cause of primary ovarian insufficiency (POI) in
more women by extensive screening? SUMMARY ANSWER Adding next generation …

Premature ovarian insufficiency (POI) is a clinically heterogeneous disease that may
seriously affect the physical and mental health of women of reproductive age. POI primarily …

About 10% of reproductive-aged couples suffer from infertility. However, the genetic causes
of human infertility cases are largely unknown. Meiosis produces haploid gametes for …

Purpose Premature ovarian insufficiency (POI) is a heterogeneous disorder characterized by
the cessation of menstrual cycles before the age of 40 years due to the depletion or …

Background Premature ovarian insufficiency refers to the loss of ovarian function before 40
years of age. The etiology is heterogeneous, and genetic factors account for 20–25% of …

Primary ovarian insufficiency (POI) is a heterogeneous disease resulting from non-functional
ovaries in women before the age of 40. It is characterized by primary amenorrhea or …

Infertility affects couples worldwide. Premature ovarian insufficiency (POI) refers to loss of
ovarian function before 40 years of age and is a contributing factor to infertility. Several case …