Chronic obstructive pulmonary disease is a major health problem with a high prevalence, a
rising incidence, and substantial morbidity and mortality. Its course is punctuated by acute …

Chronic obstructive pulmonary disease (COPD) is a complex, heterogeneous, progressive
inflammatory airway disease associated with a significant impact on patients' lives, including …

Rationale: Eosinophils drive pathophysiology in stable and exacerbating eosinophilic
asthma, and therefore treatment is focused on the reduction of eosinophil numbers …

Chronic obstructive pulmonary disease (COPD) is a highly heterogeneous disease, and
metabolomics plays a hub role in predictive, preventive, and personalized medicine (PPPM) …

Oxidative stress is an outcome of imbalance in production vis-à-vis removal of reactive
oxygen species (ROS). The critical role of oxidative stress in several chronic inflammatory …

In recent years, tremendous efforts have been devoted to characterizing the inflammatory
processes in chronic obstructive pulmonary disease (COPD) in order to provide more …

Purpose Fractional exhaled nitric oxide (FENO50) level and peripheral blood eosinophil
count may serve as indicators of airway eosinophilia. The aim of this study was to estimate …

Exhaled nitric oxide fraction (F ENO) values can be easily measured using portable
analysers and are a surrogate marker of airway eosinophilia. F ENO may be useful in …

Background Measurement of sputum is frequently used to define airway inflammatory
subtypes. The venous blood cell is a reliable and simple biomarker, may be used as an …

Abstract Chronic Obstructive Pulmonary Disease (COPD) has been traditionally associated
with neutrophilic inflammation of the bronchi. Studies from the early 1990s demonstrated …