Structure and activity of the type VI secretion system
Y Cherrak, N Flaugnatti, E Durand, L Journet… - Microbiology …, 2019 - Am Soc Microbiol
The type VI secretion system (T6SS) is a multiprotein machine that uses a spring-like
mechanism to inject effectors into target cells. The injection apparatus is composed of a …
mechanism to inject effectors into target cells. The injection apparatus is composed of a …
T6SS mediated stress responses for bacterial environmental survival and host adaptation
The bacterial type VI secretion system (T6SS) is a protein secretion apparatus widely
distributed in Gram-negative bacterial species. Many bacterial pathogens employ T6SS to …
distributed in Gram-negative bacterial species. Many bacterial pathogens employ T6SS to …
Biogenesis and structure of a type VI secretion baseplate
Y Cherrak, C Rapisarda, R Pellarin, G Bouvier… - Nature …, 2018 - nature.com
To support their growth in a competitive environment and cause pathogenesis, bacteria
have evolved a broad repertoire of macromolecular machineries to deliver specific effectors …
have evolved a broad repertoire of macromolecular machineries to deliver specific effectors …
Cryo-EM structure and assembly of an extracellular contractile injection system
F Jiang, N Li, X Wang, J Cheng, Y Huang, Y Yang… - Cell, 2019 - cell.com
Contractile injection systems (CISs) are cell-puncturing nanodevices that share ancestry
with contractile tail bacteriophages. Photorhabdus virulence cassette (PVC) represents one …
with contractile tail bacteriophages. Photorhabdus virulence cassette (PVC) represents one …
Live cell dynamics of production, explosive release and killing activity of phage tail-like weapons for Pseudomonas kin exclusion
Interference competition among bacteria requires a highly specialized, narrow-spectrum
weaponry when targeting closely-related competitors while sparing individuals from the …
weaponry when targeting closely-related competitors while sparing individuals from the …
The depths of virus exaptation
EV Koonin, M Krupovic - Current Opinion in Virology, 2018 - Elsevier
Highlights•Viruses and their components are repeatedly exapted for diverse host
functions.•Virus components are often exapted to function in antiviral defense.•Defective …
functions.•Virus components are often exapted to function in antiviral defense.•Defective …
The gp27-like hub of VgrG serves as adaptor to promote Hcp tube assembly
MG Renault, JZ Beas, B Douzi, M Chabalier… - Journal of molecular …, 2018 - Elsevier
Contractile injection systems are multiprotein complexes that use a spring-like mechanism to
deliver effectors into target cells. In addition to using a conserved mechanism, these …
deliver effectors into target cells. In addition to using a conserved mechanism, these …
Characterization of multiple type-VI secretion system (T6SS) VgrG proteins in the pathogenicity and antibacterial activity of porcine extra-intestinal pathogenic …
B Zong, Y Zhang, X Wang, M Liu, T Zhang, Y Zhu… - Virulence, 2019 - Taylor & Francis
Porcine extra-intestinal pathogenic Escherichia coli (ExPEC) causes great economic losses
to the pig industry and poses a serious threat to public health worldwide. Some secreted …
to the pig industry and poses a serious threat to public health worldwide. Some secreted …
Coevolution-guided mapping of the type VI secretion membrane complex-baseplate interface
E Vanlioğlu, YG Santin, I Filella-Merce… - Journal of Molecular …, 2023 - Elsevier
The type VI secretion system (T6SS) is a multiprotein weapon evolved by Gram-negative
bacteria to deliver effectors into eukaryotic cells or bacterial rivals. The T6SS uses a …
bacteria to deliver effectors into eukaryotic cells or bacterial rivals. The T6SS uses a …
Fur-Dam Regulatory Interplay at an Internal Promoter of the Enteroaggregative Escherichia coli Type VI Secretion sci1 Gene Cluster
YR Brunet, CS Bernard, E Cascales - Journal of Bacteriology, 2020 - Am Soc Microbiol
The type VI secretion system (T6SS) is a weapon for delivering effectors into target cells that
is widespread in Gram-negative bacteria. The T6SS is a highly versatile machine, as it can …
is widespread in Gram-negative bacteria. The T6SS is a highly versatile machine, as it can …