Intestinal barrier in human health and disease

N Di Tommaso, A Gasbarrini, FR Ponziani - International journal of …, 2021 - mdpi.com
The intestinal mucosa provides a selective permeable barrier for nutrient absorption and
protection from external factors. It consists of epithelial cells, immune cells and their …

Early-life interactions between the microbiota and immune system: impact on immune system development and atopic disease

K Donald, BB Finlay - Nature Reviews Immunology, 2023 - nature.com
Prenatal and early postnatal life represent key periods of immune system development. In
addition to genetics and host biology, environment has a large and irreversible role in the …

Utilization of the microbiome in personalized medicine

K Ratiner, D Ciocan, SK Abdeen, E Elinav - Nature Reviews …, 2024 - nature.com
Inter-individual human variability, driven by various genetic and environmental factors,
complicates the ability to develop effective population-based early disease detection …

The double-edged sword of probiotic supplementation on gut microbiota structure in Helicobacter pylori management

A Nabavi-Rad, A Sadeghi, H Asadzadeh Aghdaei… - Gut …, 2022 - Taylor & Francis
As Helicobacter pylori management has become more challenging and less efficient over
the last decade, the interest in innovative interventions is growing by the day. Probiotic co …

Beneficial Bacteria isolated from food in relation to the next generation of probiotics

B Sionek, A Szydłowska, D Zielińska… - Microorganisms, 2023 - mdpi.com
Recently, probiotics are increasingly being used for human health. So far, only lactic acid
bacteria isolated from the human gastrointestinal tract were recommended for human use as …

Kluyveromyces marxianus supplementation ameliorates alcohol-induced liver injury associated with the modulation of gut microbiota in mice

Y Cui, P Guo, M Ning, Y Yue, Y Yuan, T Yue - Food & Function, 2023 - pubs.rsc.org
The aim of this study was to evaluate the intervention effect of the potential probiotic
Kluyveromyces marxianus YG-4 isolated from Tibetan kefir grains on alcoholic liver disease …

Probiotics, their action modality and the use of multi-omics in metamorphosis of commensal microbiota into target-based probiotics

M Idrees, M Imran, N Atiq, R Zahra, R Abid… - Frontiers in …, 2022 - frontiersin.org
This review article addresses the strategic formulation of human probiotics and allows the
reader to walk along the journey that metamorphoses commensal microbiota into target …

Next-generation probiotics as novel therapeutics for improving human health: current trends and future perspectives

ME Abouelela, YA Helmy - Microorganisms, 2024 - mdpi.com
Next-generation probiotics (NGPs) represent an innovative group of beneficial bacteria that
are currently undergoing research and development. NGPs are designed not only for …

Gut microbiome as a therapeutic target for liver diseases

TP Singh, S Kadyan, H Devi, G Park, R Nagpal - Life Sciences, 2023 - Elsevier
The prominent role of gut in regulating the physiology of different organs in a human body is
increasingly acknowledged, to which the bidirectional communication between gut and liver …

A Novel Probiotic Bacillus subtilis Strain Confers Cytoprotection to Host Pig Intestinal Epithelial Cells during Enterotoxic Escherichia coli Infection

S Sudan, X Zhan, J Li - Microbiology Spectrum, 2022 - Am Soc Microbiol
Enteric infections caused by enterotoxic Escherichia coli (ETEC) negatively impact the
growth performance of piglets during weaning, resulting in significant economic losses for …