The culmination of decades of research on humanized mice is leading to advances in our
understanding of human haematopoiesis, innate and adaptive immunity, autoimmunity …

Pro-angiogenic bone marrow (BM) cells include subsets of hematopoietic cells that provide
vascular support and endothelial progenitor cells (EPCs), which under certain permissive …

Human clinical trials in type 1 diabetes (T1D) patients using mesenchymal stem cells (MSC)
are presently underway without prior validation in a mouse model for the disease. In …

As an archetype of human adult stem cells that can readily be harvested, enriched and
expanded in vitro, mesenchymal stromal cells (MSC) have been reported to be of …

Mesenchymal stem cells (MSC) represent a type of adult stem cells that can easily be
isolated from various tissues and expanded in vitro. Past reports on their pluripotency and …

In this study the time course of homing and the body distribution of systemically delivered
bone marrow mesenchymal stem cells (BM-MSCs) after myocardial infarction (MI) were …

During post-natal maturation of the mammalian heart, proliferation of cardiomyocytes
essentially ceases as cardiomyocytes withdraw from the cell cycle and develop blocks at the …

Background: Umbilical cord blood (UCB) is an easily accessible alternative source for
multipotent mesenchymal stromal cells (MSCs) and is generally believed to provide MSCs …

Background Research on mesenchymal stromal cells has created high expectations for a
variety of therapeutic applications. Extensive propagation to yield enough mesenchymal …

There is a growing need for effective animal models to carry out experimental studies on
human hematopoietic and immune systems without putting individuals at risk. Progress in …