The dynamic lung microbiome in health and disease
JG Natalini, S Singh, LN Segal - Nature Reviews Microbiology, 2023 - nature.com
New methods and technologies within the field of lung biology are beginning to shed new
light into the microbial world of the respiratory tract. Long considered to be a sterile …
light into the microbial world of the respiratory tract. Long considered to be a sterile …
Idiopathic pulmonary fibrosis: Disease mechanisms and drug development
P Spagnolo, JA Kropski, MG Jones, JS Lee… - Pharmacology & …, 2021 - Elsevier
Idiopathic pulmonary fibrosis (IPF) is a chronic progressive disease of unknown cause
characterized by relentless scarring of the lung parenchyma leading to reduced quality of life …
characterized by relentless scarring of the lung parenchyma leading to reduced quality of life …
Idiopathic pulmonary fibrosis: an update on pathogenesis
Q Mei, Z Liu, H Zuo, Z Yang, J Qu - Frontiers in pharmacology, 2022 - frontiersin.org
Idiopathic pulmonary fibrosis (IPF) is a progressive, lethal fibrotic lung disease that occurs
primarily in middle-aged and elderly adults. It is a major cause of morbidity and mortality …
primarily in middle-aged and elderly adults. It is a major cause of morbidity and mortality …
Idiopathic pulmonary fibrosis: state of the art for 2023
AJ Podolanczuk, CC Thomson… - European …, 2023 - Eur Respiratory Soc
Idiopathic pulmonary fibrosis (IPF) is a progressive fibrotic lung disease characterised by
worsening respiratory symptoms and physiological impairment. Increasing awareness of the …
worsening respiratory symptoms and physiological impairment. Increasing awareness of the …
The lung microbiome: progress and promise
SA Whiteside, JE McGinniss… - The Journal of Clinical …, 2021 - Am Soc Clin Investig
The healthy lung was long thought of as sterile, but recent advances using molecular
sequencing approaches have detected bacteria at low levels. Healthy lung bacteria largely …
sequencing approaches have detected bacteria at low levels. Healthy lung bacteria largely …
Immune dysregulation as a driver of idiopathic pulmonary fibrosis
K Shenderov, SL Collins, JD Powell… - The Journal of clinical …, 2021 - Am Soc Clin Investig
Idiopathic pulmonary fibrosis (IPF) affects hundreds of thousands of people worldwide,
reducing their quality of life and leading to death from respiratory failure within years of …
reducing their quality of life and leading to death from respiratory failure within years of …
Lung microbiota predict clinical outcomes in critically ill patients
RP Dickson, MJ Schultz, T Van Der Poll… - American journal of …, 2020 - atsjournals.org
Rationale: Recent studies have revealed that, in critically ill patients, lung microbiota are
altered and correlate with alveolar inflammation. The clinical significance of altered lung …
altered and correlate with alveolar inflammation. The clinical significance of altered lung …
The therapy of idiopathic pulmonary fibrosis: what is next?
V Somogyi, N Chaudhuri, SE Torrisi… - European …, 2019 - Eur Respiratory Soc
Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive, fibrosing interstitial lung
disease, characterised by progressive scarring of the lung and associated with a high …
disease, characterised by progressive scarring of the lung and associated with a high …
Pulmonary fibrosis as a result of acute lung inflammation: molecular mechanisms, relevant in vivo models, prognostic and therapeutic approaches
IA Savin, MA Zenkova, AV Sen'kova - International journal of molecular …, 2022 - mdpi.com
Pulmonary fibrosis is a chronic progressive lung disease that steadily leads to lung
architecture disruption and respiratory failure. The development of pulmonary fibrosis is …
architecture disruption and respiratory failure. The development of pulmonary fibrosis is …
In critically ill patients, anti-anaerobic antibiotics increase risk of adverse clinical outcomes
R Chanderraj, JM Baker, SG Kay… - European …, 2023 - Eur Respiratory Soc
Background Critically ill patients routinely receive antibiotics with activity against anaerobic
gut bacteria. However, in other disease states and animal models, gut anaerobes are …
gut bacteria. However, in other disease states and animal models, gut anaerobes are …