Nontuberculous mycobacterial lung disease caused by Mycobacterium avium complex - disease burden, unmet needs, and advances in treatment developments
J van Ingen, M Obradovic, M Hassan… - Expert Review of …, 2021 - Taylor & Francis
Introduction Nontuberculous mycobacterial (NTM) lung disease (LD) is the most common
clinical manifestation of NTM infection and is a growing health concern. Up to 85% of NTM …
clinical manifestation of NTM infection and is a growing health concern. Up to 85% of NTM …
[HTML][HTML] Meeting the challenges of NTM-PD from the perspective of the organism and the disease process: innovations in drug development and delivery
R van der Laan, A Snabilié, M Obradovic - Respiratory Research, 2022 - Springer
Non-tuberculous mycobacterial pulmonary disease (NTM-PD) poses a substantial patient,
healthcare, and economic burden. Managing NTM-PD remains challenging, and factors …
healthcare, and economic burden. Managing NTM-PD remains challenging, and factors …
[HTML][HTML] Advances in nanostructures for antimicrobial therapy
J Jampilek, K Kralova - Materials, 2022 - mdpi.com
Microbial infections caused by a variety of drug-resistant microorganisms are more common,
but there are fewer and fewer approved new antimicrobial chemotherapeutics for systemic …
but there are fewer and fewer approved new antimicrobial chemotherapeutics for systemic …
Anti-Porphyromonas gingivalis nanotherapy for maintaining bacterial homeostasis in periodontitis
R Chen, Y Ji, T Li, B Zhao, H Guo, Z Wang… - International Journal of …, 2023 - Elsevier
Periodontitis is caused by oral flora imbalance, which leads to immune imbalance.
Porphyromonas gingivalis is a keystone pathogen in periodontitis, causing the blooming of …
Porphyromonas gingivalis is a keystone pathogen in periodontitis, causing the blooming of …
[HTML][HTML] Targeted delivery of ZNF416 siRNA-loaded liposomes attenuates experimental pulmonary fibrosis
D Cheng, Z Li, Y Wang, H Xiong, W Sun, S Zhou… - Journal of Translational …, 2022 - Springer
Background Pulmonary fibrosis is a chronic progressive fibrotic interstitial lung disease
characterized by excessive extracellular matrix (ECM) deposition caused by activated …
characterized by excessive extracellular matrix (ECM) deposition caused by activated …
Nitric oxide-releasing prodrug for the treatment of complex Mycobacterium abscessus infections
RA McDonald, SG Nagy, M Chambers… - Antimicrobial Agents …, 2024 - Am Soc Microbiol
Non-tuberculosis mycobacteria (NTM) can cause severe respiratory infection in patients with
underlying pulmonary conditions, and these infections are extremely difficult to treat. In this …
underlying pulmonary conditions, and these infections are extremely difficult to treat. In this …
Liposome-siderophore conjugates loaded with moxifloxacin serve as a model for drug delivery against Mycobacterium tuberculosis
CM Ribeiro, CA Roque-Borda, MC Franzini… - International Journal of …, 2024 - Elsevier
Tuberculosis (TB) is an infectious disease that annually affects millions of people, and
resistance to available antibiotics has exacerbated this situation. Another notable …
resistance to available antibiotics has exacerbated this situation. Another notable …
[HTML][HTML] Nanomaterials-assisted gene editing and synthetic biology for optimizing the treatment of pulmonary diseases
L Lei, W Pan, X Shou, Y Shao, S Ye, J Zhang… - Journal of …, 2024 - Springer
The use of nanomaterials in gene editing and synthetic biology has emerged as a pivotal
strategy in the pursuit of refined treatment methodologies for pulmonary disorders. This …
strategy in the pursuit of refined treatment methodologies for pulmonary disorders. This …
Liposomal amikacin and Mycobacterium abscessus: intimate interactions inside eukaryotic cells
V Le Moigne, S Blouquit-Laye… - Journal of …, 2022 - academic.oup.com
Abstract Background Mycobacterium abscessus (Mabs), a rapidly growing Mycobacterium
species, is considered an MDR organism. Among the standard antimicrobial multi-drug …
species, is considered an MDR organism. Among the standard antimicrobial multi-drug …
[HTML][HTML] Real-world treatment patterns in patients with nontuberculous mycobacterial lung disease in the Netherlands based on medication dispensing data
W Hoefsloot, E Dacheva, R Van Der Laan… - BMC Pulmonary …, 2023 - Springer
Purpose Real-world data on antibiotic management of nontuberculous mycobacterial lung
disease (NTM-LD) is limited for many countries. This study aimed to evaluate real-world …
disease (NTM-LD) is limited for many countries. This study aimed to evaluate real-world …