The interplay between androgens and the immune response in polycystic ovary syndrome

S Shabbir, E Khurram, VS Moorthi, YTH Eissa… - Journal of Translational …, 2023 - Springer
Polycystic ovary syndrome (PCOS) is a metabolic-reproductive-endocrine disorder that,
while having a genetic component, is known to have a complex multifactorial etiology. As …

Mitochondrial dysfunction and chronic inflammation in polycystic ovary syndrome

SA Dabravolski, NG Nikiforov, AH Eid… - International journal of …, 2021 - mdpi.com
Polycystic ovarian syndrome (PCOS) is the most common endocrine–metabolic disorder
affecting a vast population worldwide; it is linked with anovulation, mitochondrial …

Insulin resistance, autophagy and apoptosis in patients with polycystic ovary syndrome: Association with PI3K signaling pathway

C Tong, Y Wu, L Zhang, Y Yu - Frontiers in Endocrinology, 2022 - frontiersin.org
Polycystic ovary syndrome (PCOS) is a disease in which endocrine metabolic abnormalities
coexist with reproductive system abnormalities, with the main clinical manifestations …

Arterial hypertension in women: state of the art and knowledge gaps

N Chapman, SM Ching, AO Konradi, AM Nuyt… - …, 2023 - Am Heart Assoc
Hypertension is the leading risk factor for cardiovascular disease and premature death
among women globally. However, there is a fundamental lack of knowledge regarding the …

Serum granulosa cell-derived TNF-α promotes inflammation and apoptosis of renal tubular cells and PCOS-related kidney injury through NF-κB signaling

H Ye, Y Song, W Ye, C Xiong, J Li, J Miao… - Acta Pharmacologica …, 2023 - nature.com
Polycystic ovary syndrome (PCOS) is a disorder with endocrinal and metabolic problems in
reproductive aged women. Evidence shows that PCOS is in a high prone trend to develop …

Heavy metals and essential elements in association with oxidative stress in women with polycystic ovary syndrome—a systematic review

T Srnovršnik, I Virant-Klun, B Pinter - Antioxidants, 2023 - mdpi.com
Altered levels of heavy metals and essential elements have been associated with oxidative
stress (OS) and metabolic and hormonal changes in women with polycystic ovary syndrome …

Chemical Characterization and Ameliorating Effect of Centratherum anthelminticum Extract against Polycystic Ovary Syndrome in Wistar Rats

M Shoaib, A Saleem, A Zeb, MI Khan… - International Journal of …, 2023 - Wiley Online Library
Polycystic ovary syndrome (PCOS) in females is an endocrine pathological condition of
reproductive age which is usually caused by insulin resistance, hyperlipidemia, and …

Review of novel potential insulin resistance biomarkers in PCOS patients—The debate is still open

J Kruszewska, H Laudy-Wiaderny… - International journal of …, 2022 - mdpi.com
Research on proteins and peptides that play roles in metabolic regulation, which may be
considered potential insulin resistance markers in some medical conditions, such as …

Circulating inflammatory cytokines and female reproductive diseases: a Mendelian randomization analysis

Y Lin, G Wang, Y Li, H Yang, Y Zhao… - The Journal of Clinical …, 2023 - academic.oup.com
Context Extensive studies have provided considerable evidence suggesting the role of
inflammation in the development of female reproductive diseases. However, causality has …

Inflammasomes: Cause or consequence of obesity‐associated comorbidities in humans

AD Herrera‐Martínez, V Herrero‐Aguayo… - …, 2022 - Wiley Online Library
Inflammasomes are multiprotein intracellular complexes composed of innate immune
system receptors and sensors; they activate the inflammatory cascade in response to …