Cardiovascular diseases (CVD) are the leading cause of death worldwide. Since the
establishment of the “lipid hypothesis”, according to which, cholesterol level is directly …

One of the greatest burdens on the healthcare systems of modern civilization is
cardiovascular diseases (CVDs). Therefore, the medical community is looking for ways to …

Cholesterol remains a vital molecule required for life; however, increasing evidence exists
implicating cholesterol in cancer development and progression. Numerous studies …

The role of estrogen receptors (ERs) in breast cancer is of great importance in both clinical
practice and scientific exploration. However, around 15–30% of those affected do not see …

Colorectal cancer (CRC), a tumor of the digestive system, is characterized by high
malignancy and poor prognosis. Currently, targeted therapy of CRC is far away from …

The development of novel drugs from basic science to clinical practice requires several
years, much effort, and cost. Drug repurposing can promote the utilization of clinical drugs in …

Background The immune system plays a pivotal role in the initiation, evolution, invasion and
metastasis of cancer. Therapeutics aiming at modulating or boosting anticancer immune …

Statins and non-statin medications used for the management of dyslipidemia have been
shown to possess antitumor properties. Since the use of these drugs has steadily increased …

Autophagy is a process that is characterized by the destruction of redundant components
and the removal of dysfunctional ones to maintain cellular homeostasis. Autophagy …

Background: The cancers of the digestive tract, including colorectal cancer (CRC), gastric
cancer, and esophageal cancer, are part of the most common cancers as well as one of the …